English name: 1- ethyl -3-(3-dimensional aminopropyl) carbodiimide hydrochloride.
English alias: EDC. Hydrochloric acid, EDAC, EDCI, EDC, hydrochloride; ; WSC； hydrochloride; N- ethyl -N '-(3- dimethylaminopropyl) carbodiimide hydrochloride.
The chemical molecular formula is c8 h17n3 HCl.
Extended data
EDCI features: white crystalline powder, easy to absorb moisture. Solubility in water >: 20g/ 100ml, soluble in ethanol. It needs to be stored and transported in inert gas at 2-8℃
Use of EDCI:
1, EDCI is a water-soluble carbodiimide, which is used as an activating reagent for carboxyl groups in amide synthesis, and also used to activate phosphate groups to cross-link protein with nucleic acids to prepare immunoconjugates. When used, the pH range is 4.0-6.0, and it is often used with N- hydroxysuccinimide (NHS) or N- hydroxythiosuccinimide to improve the coupling efficiency.
2. In organic chemistry, EDCI and catalyst 4- dimethylaminopyridine (DMAP) are used for esterification of carboxylic acid and alcohol.
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