North China Pharmaceutical PatentNo. zl2006 1008 1498.4

This invention patent is still valid.

Mixture of recombinant human albumin and yeast enzyme, composition contain that mixture, preparation method and application thereof

The application number is CN2006 1008 1498.4, and the application date is may 24th, 2006.

Publication (announcement)No. CN 1875920A Publication (announcement) date 2006. 12. 13.

Right of validity of current legal status authorization

Classification number A 61K 8/99 (2006.438+0); a 6 1k 8/64(2006.0 1); a 6 1k 8/06(2006.0 1); a 6 1q 19/00(2006.0 1); C 12P2 1/02

Applicant (patent right): North China Pharmaceutical Group New Drug Research and Development Co., Ltd.;

Address: 0500 15, No.388 Heping East Road, Shijiazhuang, Hebei

Inventor (designer) Li Meiyan; Wang Huijuan; Jia; White jade; Meng Yajuan; Ren Liwei; Shen Xudong; JUNG WOO; Chen Lihua; Gao Jian; Cang Jiyong

Priority 2005.05.31cn200510012559.7

Patent agent

abstract

The invention discloses a mixture of recombinant human albumin and yeast enzyme, and the mixture of recombinant human albumin and yeast enzyme can be directly obtained through a simple and effective separation and extraction process of Pichia pastoris containing human albumin gene constructed by a certain scale of fermentation culture and PCR technology, which can be used as a large-scale production process. The invention also discloses a composition containing the mixture and its application in skin moisturizing, anti-wrinkle, wrinkle removal and whitening.