The hollow fiber membrane used in the dialyzer is a polysulfone hollow fiber membrane developed and produced by our company (a Chinese patent has been applied for). The membrane has high anti-destruction performance; the micropore size of the membrane is easy to control and has a wide range of applications; it has high chemical stability; it can withstand a variety of reagents and r-ray sterilization; its glass transition temperature (Tg) is high, and it can Uses high-temperature steam for sterilization; the inner and outer surfaces of the membrane are smooth and will not easily damage tangible objects in the blood; easy to rinse; residual blood is small; has excellent blood compatibility and anticoagulant properties; has excellent permeability to creatinine, urea and other substances .
A hemodialyzer assembled from polysulfone hollow fiber membranes has been sterilized by ethylene oxide gas or r-rays. This product is non-pyrogenic. It can be used as a disposable medical product for patients with acute and chronic renal failure caused by various reasons, and can also be used to rescue the wounded and poisoned patients with severe trauma.
Main technical indicators
1. The technical specifications of various models and specifications are as follows:
Model specifications
REGI 80
REGI 120
REGI 130
REGI 140
Membrane material
Polysulfone
Dialysis area (m2)
0.8
1.2
1.3
1.4
Membrane inner diameter (μm)
210
Blood chamber volume (ml )
≤70
≤90
≤95
≤100
Clear rate
(ml/min)
Test conditions
QB=200mL/min QD=500mL/min TMP=100mmHg
Urea
< p> 155170
180
187
Creatinine
150
160
170
175
Ultrafiltration coefficient (ml/kPa.h)
25
37
41
45
Maximum operating pressure KPa/ mmHg
66.5 / 500
Maximum flow rate (ml /min)
Blood 300, dialysate 500
Sterilization method and validity period
EO or r-ray sterilization, validity period 2 years
Instructions for use
1. Connection of hemodialyzer and catheter: Take out the hemodialyzer from the complete packaging bag, and connect the arterial pipeline, venous pipeline and filtrate pipeline to the corresponding parts of the dialyzer. Take over. Install the dialyzer with various pipes connected to the dialyzer fixture.
2. Fill the device with physiological saline (more than 1000mL) to remove residual ethylene oxide gas in the dialyzer and air bubbles in the device and catheter.
3. Heparinize the dialyzer and blood catheter with saline containing heparin (1000 IU/ML).
4. Connect the dialysate system (bottom in and top out) and circulate for several minutes; connect the arteries and veins (blood flow from top to bottom) for dialysis.
5. Monitor the dialysis process at any time and add heparin timely to ensure that coagulation does not occur and to avoid bleeding caused by too much heparin.
6. After dialysis, connect normal saline (500 mL) to the blood inlet, and gradually inject the residual blood in the dialyzer back into the body.
Precautions during use and storage
1. Before using the product, you should strictly check whether the packaging bag is damaged. If it is damaged, it is prohibited to use it. Check whether the disinfection date is within the safe use period.
2. Strictly perform aseptic procedures when connecting blood pipes and use them as soon as possible.
3. During the pre-flushing and flushing processes, care must be taken to strictly prohibit air from entering the dialyzer and blood pipes. During the flushing process, liquid may be discharged from the dialysate port.
4. The transmembrane pressure should be strictly kept below 66.5 kPa (500mmHg). Unnecessary pressure should not be applied to the dialyzer and blood pipes to prevent leakage and connection parts from falling off.
5. This product is for one-time use and must be destroyed after use.
6. Warning: Please use it strictly in accordance with the instructions. The manufacturer will not bear any responsibility for the consequences of violating the operation.
7. Storage requirements: Store in a dry environment of 0-400C. Direct sunlight, violent vibration and the intrusion of harmful gases should be avoided.
Complications and treatment methods
Hemodialysis (HD) treatment has gone through a certain period of development. Dialysis technology has become increasingly mature and equipment has become increasingly perfect. Therefore, complications that may occur during dialysis are relatively Rare.
1. Hypotension: Hypotension is a relatively common complication of dialysis, usually characterized by dizziness, dizziness, sweating, and yawning. The cause of hypotension is generally insufficient effective blood volume. The prevention and treatment methods are to prevent excessive ultrafiltration, appropriate water and sodium intake, and regular adjustment of dry body weight.
2. Arrhythmia: Maintenance dialysis patients may develop arrhythmia during dialysis. Common causes include hyperkalemia, hypokalemia, myocardial disease, coronary heart disease, etc. Treatment should be based on different causes and types of arrhythmia; The potassium concentration of the dialysate should be selected appropriately. Patients with severe anemia should undergo blood transfusion or EPO. ECG monitoring should be performed during dialysis, and antiarrhythmic drugs should be given promptly.
3. Nausea and vomiting: Nausea and vomiting may occasionally occur during dialysis. Common causes include osmotic pressure imbalance between plasma and dialysate at the beginning of dialysis, hypotension and certain drugs. Treatment should focus on the cause. If dialysis is too fast, it can be slowed down appropriately. To treat hypotension, check water quality frequently, prevent hard water from preparing dialysate, and give antiemetics and sedatives for symptomatic treatment.