How do allergic diseases occur? First, it is caused by having an allergic constitution and being exposed to various allergens in the environment, such as pollen, dust, mites, etc., which causes the body to produce a large amount of immunoglobulin E, thereby triggering an inappropriate immune response. If the inflammatory reaction caused by allergies occurs in the nasal cavity, it causes allergic rhinitis; when it occurs in the trachea and bronchi, it causes asthma; when it occurs on the skin, it causes allergic dermatitis; when it occurs in the gastrointestinal tract, it causes allergic gastroenteritis. The clinical manifestations of allergic diseases are diverse and complex, with both systemic symptoms and local manifestations. The clinical manifestations may vary at different stages, locations, and environments and can be converted into each other. Clinically, some patients often suffer from multiple allergic diseases at the same time, such as allergic rhinitis, bronchial asthma, atopic dermatitis, etc. Sometimes at different periods or at different ages, the clinical manifestations can be converted or complicated in different organs or systems. For example, about 60% of allergic rhinitis patients will continue to develop asthma after a certain age. Many asthma patients have suffered from asthma after birth. There are infant eczema (commonly known as ringworm) and so on. Why do these people suffer from this disease? One is genetic factors, which is currently considered to be a polygenic inheritance. If one parent is affected, the potential incidence rate in the next generation is 40%; if both parents are affected, the potential incidence rate in the next generation is 60%. Another is environmental factors, which may play a more important role. Relevant data show that the incidence of allergic diseases increased nearly eight times in the 1990s compared with the 1920s. The reasons for this increase are mainly related to industrialization, modernization and the improvement of living standards, such as the extensive application of air conditioners, automobile exhaust, carpets, new building materials, keeping pets, non-breastfeeding of newborns, changes in dietary structure, artificial food and food additives etc. Allergic diseases are characterized by the presence in the serum of patients of a very small amount of specific immunoglobulin E. This protein is characterized by being cytophilic, that is, it can bind to the two main types of sensitized cells, mast cells and basophils. On the surface of sex cells, when allergic substances enter the body again, they can combine with specific immunoglobulin E and cause the above two cells to release inflammatory mediators, causing increased vascular permeability, hypersecretion of glands, smooth muscle contraction, and Eosinophils increase in blood and tissues, and eosinophils can release toxic proteins, causing tissue inflammation (allergic inflammation), leading to a series of clinical symptoms. Allergic rhinitis – “Australia leads the world with its nose” Allergic rhinitis is the most common allergic disease. The incidence of allergic rhinitis has increased significantly in recent decades. It is estimated that the average incidence rate worldwide has reached 25%, especially It is even more significant in developed countries, reaching astonishing levels. An international epidemiological survey of allergic diseases found that the countries and regions with the highest incidence rates are Australia, Hong Kong, New Zealand, South Korea, Taiwan, Thailand, Canada, the United Kingdom and the United States (allergic rhinitis is most common in Chicago and Seattle). The incidence rates were 34% and 41% respectively). The incidence rate in China has also increased significantly in recent years, especially in developed coastal areas. The adult incidence rate of rhinal allergy in Australia reaches 40%, which is nearly double the world average incidence rate of 25%, ranking first in the world. People even jokingly say that "Australia leads the world with its nose." For the treatment of allergic rhinitis (commonly known as nasal sensitivity), Western medicine commonly uses antihistamines and steroid sprays. Although they are very effective in the short term, they have no long-term efficacy, cumulative effect, and no preventive effect. They require lifelong medication, and there is a certain risk. side effects. Due to the limitations of chemical drugs in treating the symptoms but not the root cause, and the current trend of returning to nature, more and more people are tending to use natural therapies and herbal preparations instead of relying entirely on chemicals. Under the above circumstances, the nasal allergy team of the University of Sydney in Australia actively carried out special research on natural medicines for the treatment of allergic diseases, and made a breakthrough. It successfully developed a new natural anti-allergic medicine - Biemin Capsule, which provides patients with allergic rhinitis with "farewell to sensitivity". It provides new hope and opens up new ways and targets for the treatment and research of allergies.
Biemin Capsule – The international first Biemin Capsule is the first in the world, and it is still the only one in Western countries that has been proven by strictly randomized, double-blind, placebo-controlled scientific clinical trials to treat nasal allergy. Natural pharmaceutical preparations with indeed significant curative effects have obtained invention patent certificates from Australia, the United States, China, Singapore and other countries. Currently, there are no natural pharmaceutical preparations for nasal allergy that have been proven to be effective through rigorous scientific clinical trials in the world.
Western natural medicines for treating nasal allergies are mainly garlic and horseradish. Their efficacy is only speculated based on traditional usage, and there is no scientific clinical evidence. Although there are various types of anti-allergic traditional Chinese medicines circulating on the market, they have not been rigorously clinically verified by modern medicine and lack reliable scientific basis. Therefore, their efficacy is uncertain and cannot be recognized by the Western medical community. Under this circumstance, the Rhinal Allergy Special Group of the University of Sydney compiled a large amount of medical literature, conducted strict comparison and screening, and combined with Dr. Hu Guorang's long-term allergy research and clinical experience, actively launched clinical research on the treatment of nasal allergy with natural drugs. The University of Sydney Teaching Hospital has launched and completed a randomized, double-blind, placebo-controlled clinical trial of secondary "Biemin" capsules in the treatment of perennial allergic rhinitis.
Second clinical trials have shown that the effective rate of Biemin Capsules in treating allergic rhinitis is 86% - 90%, and the effective rate is over 60%. This result is basically the same as the efficacy of Western antihistamines. What's more valuable is that Biemin Capsule can also significantly reduce recurrences and show long-term efficacy and preventive effects. This is a unique feature that current chemical drugs do not have.
After three months of continuous medication, the five most common symptoms of allergic rhinitis, including sneezing, runny nose, nasal itching, nasal congestion and eye itching, were significantly relieved, especially sneezing. , the effect is most obvious.
Even one year after stopping taking the drug, the patient still maintained more than 50% of the efficacy. This is the first time that modern scientific methods recognized by Western academic circles have been used to prove the long-term efficacy of natural medicines. What is more significant is that continuous use has a significant cumulative effect on the curative effect, that is, the longer it is taken, the better the effect. If you insist on taking the medicine for three months or more every year for three consecutive years, you are expected to be clinically cured. This is also Currently, antihistamines and steroid hormones are not available. This important role of "Biemin" capsule has rewritten the history of "treating the symptoms but not the root cause" of allergic rhinitis.
What is particularly significant is that experimental studies conducted simultaneously with clinical trials further prove that "Biemin" capsules can significantly reduce and clear the allergic antibody IgE in the blood, improve the body's own immune regulation ability, and help Restore the internal balance of the body, strengthen the body's constitution, and regain control of out-of-control immune regulation, thereby achieving the effects of prevention, health care, and long-term peace and stability. This is also the fundamental reason why "Biemin" capsules can "eliminate the root cause." "Biemin" capsules extracted from 11 kinds of herbs do not contain any western medicine or animal ingredients. Its safety has been strictly reviewed by the Australian Federal Drug Administration. It has been carefully observed in clinical trials and has no side effects. Animal toxicology tests have also proven Very safe. After being put on the market, it has been used by tens of thousands of patients and no side effects have been found, indicating that "Biemin" capsules can be taken with confidence. In addition, according to clinical observations, "Biemin" capsules also have good effects on other types of allergies, such as asthma, food allergies, etc.
Biemin Capsule – Going global. The research work of “Biemin” has been widely valued and recognized by the international academic community. It has been presented to large-scale international academic conferences in Washington, San Diego, Australia, Sydney, Australia, and Beijing, China, six times. The reports delivered at the conference have attracted unanimous praise and attention from the participating scholars every time. In recent years, papers on allergy research have been published in full in authoritative medical journals in the United States and Europe, ending a history of more than 30 years in which there was no article on the clinical effectiveness of natural medicines in the treatment of allergic rhinitis in English literature. Filled a gap. The Director of the Clinical Research Department of the National Center for Complementary and Alternative Medicine of the National Institutes of Health, the highest medical and health research institution in the United States, spoke highly of the research on Biemin, calling it the most detailed and in-depth research report on traditional Chinese medicine that he has ever seen. He also believes that it will clearly prove to be the most effective treatment for nasal allergies ever discovered. Biemin Capsules – Entering the market The development of Biemin Capsules took 8 years of unremitting efforts and passed different stages such as secondary clinical trials, animal toxicology and pharmacology tests, drug quality standards and stability tests, and production process research, as well as The University of Sydney Drug Committee, Ethics Committee, Australian Federal Drug Administration and other departments went through a series of extremely time-consuming, complex, cumbersome and strict approvals during the research and marketing process, and finally became the first pure natural antibiotic successfully developed in a Western country. Nasal Sensitivity Medication.
Biemin Capsules are produced by a large pharmaceutical factory with Australian GMP standards. They have strict quality control and specialize in research and design of a unique extraction and production process, so that the effective content is more than 5 times that of herbal medicines produced by ordinary extraction. From medicinal materials to finished products, everything is After strict testing, the quality remains stable and reliable. At present, Biemin Capsules have been fully launched in Australia and have entered mainstream sales channels. They are sold throughout Australia through multiple distributors, benefiting the majority of sensitive patients.
The paper on the clinical research of Biemin <
In recent years, the above-mentioned papers with Dr. Hu Guorang as the first author have been published in full in the authoritative medical journals ANNALS OF ALLERGY, ASTHMA, & IMMUNOLOGY and ALLERGY & CLINICAL IMMUNOLOGY INTERNATIONAL in the United States and Europe respectively, ending more than 30 years ago. In the English dictionary, there is no article on the clinical effectiveness of traditional Chinese medicine in the treatment of allergic rhinitis. This fills a gap and achieves a substantial breakthrough for traditional Chinese medicine to the world.
The Director of the Clinical Research Department of the American Center for Complementary and Alternative Medicine of the National Institutes of Health (NIH), the highest medical and health research institution in the United States, spoke highly of Dr. Hu Guorang’s paper on allergy research and called it The most detailed and in-depth research report on traditional Chinese medicine he has ever seen. (The work may represent the most comprehensive evaluation yet of any Traditional Chinese Medicine.) He also believes that Biemin will clearly prove to be the most effective treatment for nasal allergies discovered to date. (Biminne may well prove to be the single most effective treatment for allergic rhinitis discovered.)