(2) separation and preparation of active ingredients in natural medicines;
(3) Bioorganic synthesis of important pharmaceutical intermediates;
(4) Design and synthesis of drug molecules;
(5) Fingerprint analysis of traditional Chinese medicine and the structure and activity of active small molecules of traditional Chinese medicine;
(6) Bioorganic synthesis of drugs and drug intermediates;
(7) Development and utilization of natural biological resources
(8) Projects undertaken by the new drug delivery system:
Key projects of National Natural Science Foundation of China:
2003-2006: (No.:20235020) Study on the Analysis Method of Effective Components in Chromatographic Fingerprint of Traditional Chinese Medicine, 1.6 million Yuan, which has been concluded.
International scientific and technological cooperation project of Ministry of Science and Technology
2006-2008: (No.:2007DFA4 1090) Analysis and evaluation of active components of traditional Chinese medicine based on metabonomics, 700,000 yuan.
2008-20 10: (No.:2007DFA40680) Basic research on modernization of traditional Chinese medicine based on system biology,10.9 million.
General Project of National Natural Science Foundation of China:
1999-200 1: (No.:29735 150) Multivariate analysis method of high-dimensional data and its application in Chinese herbal medicine analysis, 280,000 yuan, completed;
2002-2004: (No.:20 175036) "Research on New Chemometrics Methods of Data Mining in Analytical Chemistry" has been completed, with a funding amount of 220,000 yuan.
Research projects entrusted by the National Pharmacopoeia Committee:
2002-2004: The fingerprint of Houttuynia cordata injection was studied and the national standard was formulated, with the amount of 1 10,000.
Hong Kong cooperation projects:
1999-2002: research on the application of chromatography in the analysis of Chinese herbal medicines, 300,000 yuan, completed;
2000-2002: High-dimensional data analysis method of chemometrics and its application in qualitative and quantitative analysis of fingerprint of traditional Chinese medicine, 250,000, completed.
2000-2004: The fingerprint analysis of Zhengqingfengtongning and Houttuynia Cordata Injection was completed, with a total amount of 6.5438+0.4 million;
Yunnan provincial development and reform commission's major key technology development project of biomedical industrialization "Rauvolfia seed selection and key technology development of industrialization" Transferable technology:
Formula and production technology of honeysuckle functional beverage based on intermolecular synergy >: Guangdong Qingyuan Datong Biotechnology Co., Ltd. switched to build a functional beverage factory with an annual output of 654.38 million tons.
Patents:
Authorized patent: detection method of Peucedanum purpurea ZL2006 10 103386.4 (Liu, Central South University)
Patent application: 1) A production method of imperatorin (2006 10 103385. x)； 2) A germinated brown rice product and its production method.
(2006 10 103384.5); 3) A nutritional powder (200710152142. X) It has the functions of balancing nutrition, losing weight and lowering blood sugar; 4) Use of acanthopanax senticosus or its aglycone with anti-inflammatory effect (20071kloc-0/98460.x); 5) Preparation of Acanthopanax senticosus or its aglycone with anti-inflammatory effect (2007/kloc-0 2007 10 198459.7).