The effects and efficacy of calf medicines, the effects and efficacy of calf medicines

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Overview of the contents of this article: 1. Effects of calf blood 2. Instructions for deproteinized calf blood extract for injection 3. What are the effects and functions of calf serum deproteinized injection? 4. How about calf cartilage protein capsules? The main ingredients of calf blood serum deproteinized injection are small molecule activation peptides and phosphoinositide oligosaccharides.

It is clinically used to treat ischemic cerebrovascular disease. It can protect brain nerve cells, reduce cerebral ischemia-reperfusion injury, improve brain oxygen and energy supply, eliminate oxygen free radicals, and promote nerve function. Cell repair and other functions.

Instructions for deproteinized calf blood extract for injection. Deproteinized calf blood extract for injection is suitable for: 1. Various diseases causing cerebral hypoxia, such as cerebral hemorrhage, cerebral embolism, encephalitis, Cerebral arteriosclerosis, Alzheimer's disease, recovery promotion, etc.

2. Acute and chronic hepatitis, infectious hepatitis, cirrhosis, etc.

The following is the instruction manual for calf blood deproteinized extract for injection that I compiled. Welcome to read it.

Product introduction of deproteinized calf blood extract for injection

Common name: Deproteinized calf blood extract for injection

Manufacturer: Heilongjiang Jiangshi Pharmaceutical Co., Ltd.

Approval number: National Drug Approval No. H20050974

Drug specification: 200mg

Drug price: RMB 0

Instructions for Deproteinized Calf Blood Extract for Injection

Trade Name New Orui

Common Name Deproteinized Calf Blood Extract for Injection

Chinese Pinyin ZhuSheYongXiaoNiuXueQuDanBaiTiQuWu

The English name is Deproteinized Calfblood Extractives for Injection

The main ingredient is extracted and refined from calf blood, which contains a variety of free amino acids and peptides.

Characteristics New Orui is a sterile white or light yellow freeze-dried product.

Indications are applicable to: 1. Various diseases that cause cerebral hypoxia, such as cerebral hemorrhage, cerebral embolism, encephalitis, cerebral arteriosclerosis, Alzheimer's disease, and promotion of resuscitation.

2. Acute and chronic hepatitis, symptomatic hepatitis, and cirrhosis.

3. Improve the quality of life of cancer patients and reduce the side effects of radiotherapy and chemotherapy.

4. Use as an energy mixture to treat myocarditis, coronary heart disease, etc.

5. Peptic ulcer, atrophic gastritis.

Dosage and Usage Xinori can be dissolved in 250ml of 0.9% sodium chloride injection or 5% glucose injection for intravenous infusion at a rate of about 2ml/min.

1. Cerebral ischemic damage: intravenous infusion of 800 to 1000 mg once a day for 2 to 3 weeks.

2. Arterial vascular disease: intravenous infusion of 800 to 1000 mg once, several times a week, and a course of treatment is four weeks.

3. Leg or other chronic ulcers and burns: 400mg intravenous infusion each time, once a day or several times a week.

Pharmacology and Toxicology Xinorui can enhance the uptake and utilization of oxygen and glucose by tissue cells, improve the hypoxic state of cells and the internal environment of the body, and increase the blood flow of the heart, brain, liver and other organs. Improve microcirculation.

Pharmacokinetics

Adverse reactions include fever, rash, hypotension and other reactions occasionally.

Precautions: If there is an inflammatory allergic reaction, the drug should be stopped immediately. People with a history of allergies should use it with caution.

It is forbidden to use if the medicine is found to be spoiled or discolored.

Contraindications 1. It is prohibited for patients with severe renal dysfunction.

2. It is prohibited for those who have allergic reactions to similar drugs.

Approval number: National Drug Approval Number H20050974

Drug standard code 86903740000029

Specification: 200mg (total solids)/bottle

Store in shading, Store in a cool place.

Valid for 2 years.

Manufacturer Heilongjiang Jiangshi Pharmaceutical Co., Ltd.

The efficacy and role of New Orui. New Orui is suitable for: 1. Various diseases that cause cerebral hypoxia, such as cerebral hemorrhage , cerebral embolism, encephalitis, cerebral arteriosclerosis, Alzheimer's disease, promotion of resuscitation, etc.

2. Acute and chronic hepatitis, symptomatic hepatitis, and cirrhosis.

3. Improve the quality of life of cancer patients and reduce the side effects of radiotherapy and chemotherapy.

4. Use as an energy mixture to treat myocarditis, coronary heart disease, etc.

5. Peptic ulcer, atrophic gastritis.

Frequently asked questions about the use of deproteinized calf blood extract for injection

Deproteinized calf blood extract for injection is a sterile freeze-dried preparation that is widely used in clinical applications. Commonly used for stroke.

The calf blood deproteinized extract for injection has significant curative effect and has few side effects on the human body.

So, what are the precautions for the deproteinized calf blood extract for injection?

The precautions for the deproteinized calf blood extract for injection are: if you have rashes or other allergies reaction, should be discontinued immediately.

Deproteinized calf blood extract for injection should not be mixed with other drugs.

The intravenous drip speed should be less than 2ml per minute.

It is prohibited to use the deproteinized calf blood extract for injection when its properties change.

Deproteinized calf blood extract for injection is clinically suitable for the treatment of stroke and brain trauma.

Peripheral vascular disease and leg ulcers.

Deproteinized calf blood extract for injection can be used for wound healing of skin transplantation, burns, scalds, erosions, wounds, bedsores, and skin and mucosal damage caused by radiation.

Deproteinized calf blood extract for injection is a sterile freeze-dried extract containing inorganic substances and small molecule organic substances prepared from fresh calf blood or serum through deproteinization, concentration, ultrafiltration or dialysis. preparation.

Deproteinized calf blood extract for injection is a protein-free calf blood extract containing low molecular peptides and nucleic acid derivatives.

Deproteinized calf blood extract for injection can improve the absorption and utilization of oxygen and glucose (independent of insulin), thereby increasing ATP turnover and providing higher energy to cells.

In situations such as reduced brain function (hypoxemia) and increased energy demand (repair, regeneration), calf blood deproteinized extract for injection can enhance energy-related functional metabolism and maintain cell function. , promoting an increase in blood supply.

What are the efficacy and functions of protein-depleted calf serum injection? The main function of calf serum deproteinized injection is to improve brain blood circulation and neurological deficits caused by nutritional disorders (ischemic damage, craniocerebral trauma).

Peripheral arterial and venous circulation disorders and the resulting arterial vascular disease and leg ulcers.

Skin transplantation, skin burns, scalds, erosion, wound healing, skin and mucosal damage caused by radiation.

Deproteinized calf blood injection is also a commonly used drug to nourish brain cells.

The main ingredients are a variety of free amino acids, small molecule peptides and oligosaccharides.

Mainly targeted at brain injuries, such as cerebral infarction, cerebral hemorrhage and other diseases.

How about calf cartilage protein capsules? Background information of calf cartilage protein capsules Internationally renowned scientists Dr. FolkmanJ and others (the first scientists in the world to propose that tumor development is related to neovascularization) in the late last century and At the beginning of the new century, he published many high-quality papers in top international journals such as Science, Cell, and Cancer Research. Experimental studies have confirmed that one or more types of bovine chondroitin have inhibitory effects on tumor neovascularization and antioxidant effects. of protein.

After three years of laboratory research, the Shanghai Cancer Institute and the Shanghai Cancer Special Project Testing Center successfully isolated and purified an active protein with anti-tumor blood vessel growth effects from calf cartilage. Comparative research with international reports this year fully proves that the experimental results of the two are consistent.

Between 2005 and 2009, in order to make this high-tech biological agent serve the majority of cancer patients as soon as possible, scientific researchers from the Shanghai Cancer Institute and the Shanghai Special Project Testing Center worked hard for nearly five years. Research and breakthrough in two core technologies for large-scale production - nano-absorption technology and lipophilic chelation technology, thus making it possible to apply calf cartilage protein, a new anti-cancer substance.

Product introduction: This product is an active glycoprotein isolated and purified from fresh calf cartilage tissue using biochemistry and molecular biology techniques. It has been fully tested by high-performance liquid phase instruments, protein analysis and experimental animals. It shows that it is a high-tech product that is naturally colorless, odorless, bromine-free, non-toxic, has low water content, has high water solubility and is easily absorbed by the human body.

It has been tested and verified by many domestic and foreign authoritative institutions such as Harvard University, MIT, University of California, Jiangsu Southeast University, Shanghai Tongji University, Fudan University and Shanghai Center for Disease Control. Calf cartilage is Protein active factor has multiple functions such as anti-tumor angiogenesis, inhibiting and killing tumor cells, especially tumor stem cells, anti-tumor invasion, antioxidant and improving immunity. It is a natural, non-toxic comprehensive biological agent and the world's first " 5A Biotherapeutics” biologics.

(For details, please refer to the review report of "Chinese Journal of Modern Internal Medicine", Volume 6, Issue 6, 2009) The calf cartilage protein developed by our center is an independently developed product and has never been available in the domestic market. There are new products on the market and not yet reported, and we have applied for invention patent protection in 2008, patent number: 200810204668.

(See Baidu Patent Search "Calf Cartilage Protein" for details) Main ingredients and content: Each capsule contains 1 mg of calf cartilage active protein. Main functional ingredients and pharmacological effects: Nearly 40 studies have been carried out by domestic and foreign scientists. Years of research have found that calf cartilage protein contains a variety of anti-cancer active factors such as CAIF, CATC, CATI, etc., which can have anti-tumor effects in many aspects. See the table below for details: Pharmacological effects of functional ingredients ▲ Anti-tumor blood vessel growth effect Bioactive factor (cartilage angiogenesis inhibitory factor, CAIF) CAIF is one of the main anti-cancer active components of calf cartilage. Research has found that it has obvious cytotoxic effects on vascular endothelial cells, and has obvious effects on the endothelial cytoskeleton system and its division and proliferation. It inhibits the movement and migration of endothelial cells, thereby inhibiting the formation of vascular endothelial buds and the formation of new blood vessels.

▲Cartilage antitumor component (CATC) CATC is another major anti-cancer active component of calf cartilage. It can inhibit the activation of plasminogen by coagulating or shrinking the tumor cytoskeleton. The synthesis of factors and tumor cell DNA can produce cytotoxic effects on tumor cells, thereby inhibiting and killing tumor cells.

In addition, studies have also found that CATC can significantly inhibit DNA synthesis in cancer stem cells.

▲Cartilage anti-tumorinvasion (CATI) CATI can be regarded as one of the active factors of anti-angiogenesis in calf cartilage. Studies have found that it can inhibit various protease activities (such as matrix metalloproteinases) , trypsin, chymotrypsin and antigenase), in vitro vascular endothelial cell proliferation activity, and tumor growth activity play an anti-tumor invasion role.

Research on cartilage matrix protein (ChM-I) found that ChM-I can directly inhibit tumor growth by inhibiting the STAT signaling pathway.

In addition, it can also prevent and treat rheumatoid arthritis by inhibiting T cell response and synovial cell proliferation.

Chondroitin sulfate Glucosamine (ChondroitinsulfateGlucosamine) are both biological immunomodulators. They have immunomodulatory effects and can improve anti-tumor immunity.

In addition, it also has the ability to enhance metabolic function and improve the repair and regeneration ability of senile normal cells, delaying aging; remove lipids and lipoproteins in the blood in the body, prevent and treat atherosclerosis; maintain cartilage flexibility, Prevent and treat rheumatoid arthritis.

Collagen promotes tissue repair ability and shortens wound healing time.

Two core mechanisms of action: 1. Inhibiting the growth of tumor blood vessels - cutting off the tumor's nutrient supply and "starving" tumor cells. The continued growth of tumors depends on the generation of new blood vessels, and the tumor angiogenesis process is stimulated by angiogenesis. Dual regulation of factors and inhibitors.

At present, the more certain tumor angiogenesis stimulating factors include vascular endothelial growth factor (VEGF), matrix metalloproteinases (MMPs), etc.

These factors bind to special receptors on nearby blood vessels, stimulating blood vessel growth.

Calf cartilage contains an active factor that inhibits tumor blood vessel growth (CAIF), which can inactivate the receptor that binds to VEGF.

At the same time, it inhibits the decomposition of MMPs No. 2, 9 and 12 on surrounding tissues and prevents the growth of new blood vessels towards tumor tissue.

Through the above-mentioned effects of CAIF active factors, the formation of the vascular endothelial cytoskeleton in the early stage of tumors is destroyed, thereby cutting off the nutritional pathways for tumor growth and causing tumors to undergo spontaneous apoptosis.

2. Suppress and kill tumor stem cells - remove the "root" of tumor onset. Tumors originate from tumor stem cells (TSC).

Cancer stem cells are like the queen bee in a bee colony. They are extremely small in number in the body. They have extremely strong ability to self-renew and differentiate heterogeneous tumor cells, and are hundreds of times more powerful than ordinary tumor cells. Its tumorigenic ability is the fundamental cause of tumor occurrence, metastasis, recurrence and drug resistance.

The anti-tumor cytokine CATC contained in calf cartilage can specifically inhibit and kill the tumor stem cells of various cancers such as lung cancer, breast cancer, liver cancer, and kidney cancer, and eliminate the root causes of tumor occurrence, thus providing the basis for cancer. A radical cure is possible.

Applicable people: Newly diagnosed tumor patients: Calf cartilage protein active factor can control tumor development, improve physical fitness, gain valuable treatment time, reduce the risk of metastasis before treatment, and prepare for comprehensive clinical treatment .

"Contain" the tumor locally, control the spread and metastasis of the tumor, and win precious time for treatment. Tumor patients undergoing surgery: Taking calf cartilage protein active factor before surgery can reduce the edema layer around the tumor, fix and shrink the mass, form a "biological envelope", and improve the surgical resection rate; taking it after surgery can accelerate wound healing and control Implant transfer caused by surgery buys time for further clinical treatment. Tumor patients in the middle and late stages who are not suitable for radiotherapy and chemotherapy: By blocking tumor blood vessels and inhibiting and killing cancer stem cells, the tumors will wither on their own, control the development of the disease, and prolong life, which brings new hope for the treatment of the middle and late stages. Cancer patients undergoing radiotherapy and chemotherapy: Combined treatment with radiotherapy and chemotherapy and calf cartilage protein active factor is the latest comprehensive treatment concept. It can plug the "stem cell loophole" in tumor treatment, effectively remove remaining cancer cells, and prevent tumor recurrence. Cancer patients in recovery: For patients in recovery, calf cartilage protein active factor forms three lines of defense: first, it inhibits the formation of new blood vessels in tumors, blocks the transfer of tumor cells and access to nutrients, so that tumor lesions cannot form; second, Eliminate hidden dangers by inhibiting stem cells and removing potential cancer cells; third, strengthen systemic immune function and eliminate mutant cells in a timely manner. High-risk groups who have been exposed to carcinogens such as dust and chemicals for a long time or have a family history of cancer: Calf cartilage protein can effectively prevent gene mutations caused by carcinogens by improving anti-tumor immunity and anti-tumor angiogenesis, thereby preventing the generation of cancer cells and achieving Cancer prevention purposes. People with vascular proliferative diseases such as breast hyperplasia: Mammary epithelial and fibrous tissue hyperplasia is the pathological basis of breast hyperplasia, and these hyperplasia require the support of the microvascular network. Calf cartilage protein can effectively inhibit the proliferation of vascular endothelial cells and destroy the establishment of the microvascular network. It also has good anti-inflammatory and swelling effects, so it has a good therapeutic effect on vascular proliferative diseases such as breast hyperplasia. People with poor physical fitness, low immunity or premature aging: Calf cartilage protein has been scientifically proven to have obvious effects of antioxidant, eliminating free radicals, delaying aging and improving immunity.

Middle-aged and elderly people can effectively improve their immunity and extend their lifespan if they insist on taking it.

Usage and dosage: 2 times a day, 2 to 3 capsules each time, taken after meals. Research unit: Shanghai Cancer Research/Institute Tumor Special Project Testing Center

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