1. What is papular urticaria?
Papular urticaria is a common allergic skin disease, which occurs in infants and adults, and is mostly related to the bites of arthropods such as mites. In summer, these arthropods breed, and after they bite the human body, they cause allergic reactions in the human body, thus causing papular urticaria. The typical skin lesions of papular urticaria are red wheal papules with a diameter of 1~2cm, which are spindle-shaped or round, and there are often black spots the size of a needle tip in the center, with papules, blisters or bullae on them, which are clustered or scattered, rarely fused, but generally asymmetrical. It can affect the trunk and limbs, and the head and face are rarely affected. Most patients have severe itching, especially at night. Repeated scratching can lead to secondary infection. Usually there are no obvious systemic symptoms, and the local superficial lymph nodes are not enlarged. Course of disease 1~2 weeks. After the damage subsides, temporary spots can be left.
Second, the occurrence of papular urticaria is directly related to external incentives.
1. People who are allergic or have a history of urticaria should pay attention to family hygiene to avoid breeding mosquitoes and mites. Allergic people should keep as few pets as possible, such as cats and dogs. If they do, they must regularly remove lice from their pets.
2. The incidence of papular urticaria is related to diet, and some foods may be the inducement. For example, fish, shrimp, seafood, wine, canned food containing artificial additives such as artificial pigments, preservatives and yeast, preserved food, beverages, etc. Can be induced. In addition, irritating foods such as too hot and sour will also reduce the digestive function of the gastrointestinal tract, making food residues stay in the intestine for too long, thus producing peptones and peptides, increasing the probability of human allergies.
3. Some drugs may cause allergies and induce papular urticaria. These drugs include penicillin, tetracycline, chloramphenicol, streptomycin, sulfonamides, polymyxin and other antibiotics, analgin, aspirin and other antipyretic and analgesic drugs.
Explanation of immunological changes that are easy to induce papular urticaria in summer: It may be that normal skin protein or denatured skin protein released after skin is stimulated by external environment stimulates human immune system to produce excessive IgE sensitized antibody in serum, and the combination of them stimulates immune cells to release inflammatory mediators such as histamine, which will make skin small blood vessels dilate and congestion, increase the intercellular space of blood vessel wall, make blood components such as plasma protein ooze from blood vessels, and local skin appears wheal or edema.
Third, papular urticaria is high, how to treat it?
First of all, the key to treat urticaria is to control the synthesis of -IgE in the body!
Antihistamines are commonly used in clinical treatment of urticaria. 1 generation Ruchlorpheniramine can effectively relieve symptoms and reduce the number of skin lesions, but it has adverse reactions such as drowsiness and anticholinergic. The second generation, such as loratadine and cetirizine hydrochloride, have weak sedative effect and are currently the first-line clinical drugs. However, we will find that antihistamines have a quick effect on urticaria, but they can be controlled after taking the medicine, and urticaria will still occur without taking the medicine. From acute urticaria to chronic urticaria, drug treatment is intermittent, and it still can't get rid of urticaria. In recent years, through the research on allergic diseases and IgE-mediated allergies, anti-IgE antibody immunotherapy has been introduced into some chronic allergic diseases, such as chronic urticaria, atopic dermatitis (eczema), perennial rhinitis and cough variant asthma.
Xinminkang anti-allergic probiotics can participate in IgE-mediated immune allergic reaction. After human dendritic cells were co-cultured with anti-allergic probiotics, anti-allergic probiotic strains with anti-allergic ability were screened by regulating the immune function of Th 1 secreted by interleukin (IL- 12). Xinmin Kang anti-allergic probiotics can use active and non-pathogenic microorganisms to improve the ecological balance of intestinal microorganisms, the largest immune organ of human body, and further promote the immune tolerance function. Lactobacillus salivarius has the international patent certification for reducing serum IgE allergic antibody, which can reduce the IgE concentration in the body after continuous supplementation for more than three months, so that allergens can not combine with IgE antibodies in the body, and thus allergic series biochemical reactions do not occur. Therefore, Xinmin Kang probiotics can resist IgE antibodies and regulate allergic constitution, while drugs can only relieve symptoms, but not regulate allergic constitution. The effective combination of anti-allergic drugs and anti-IgE antibody immunotherapy with anti-allergic probiotics can also produce ideal rehabilitation effect, which can eventually shorten the treatment course of urticaria and reduce the recurrence rate of urticaria.
Secondly, it is common in vitro prevention:
1, clean the floor mat, or replace the floor mat with a sheet. Summer sleeping mat is an important place for mites to survive. Wash the mat with boiling water regularly, and it is best to dry it in the sun. It is suggested that those who are invalid change sheets and change them regularly.
2. Wash the pillow. Pillows are also a gathering place for mites, so it is best to clean them regularly.
3. kill mosquitoes. Install screens and mosquito nets at home. The best way to kill mosquitoes is not to have stagnant water at home, and the containers that need water should be replaced frequently. There has been a lot of rain recently, so always check whether there is water on the balcony and dump it in time.
4, pets in addition to fleas. Pets often bring back fleas when they go out. The countermeasure to eliminate fleas is to keep pets clean and use shampoo and nursing liquid specially used to kill fleas. Vacuum at home, and immediately tie the bag of vacuum cleaner and throw it away, which can greatly reduce the chance of fleas growing into adults in the house during the non-adult period.
5. Reduce skin contact when playing in the wild. There are many insects in the wild, and the chances of being bitten are high. It's best to wear long-sleeved trousers with tight bottoms.