Urticaria can be divided into autoimmune urticaria, cold urticaria, solar urticaria, cholinergic urticaria, delayed stress urticaria, skin scratch and so on according to the etiology and manifestations. If urticaria wheal attacks at least twice a week for more than 6 weeks, it will become chronic urticaria. Chronic urticaria is not easy to cure, and the course of disease ranges from six months to decades. So, how to deal with urticaria effectively after it appears?
First, let's look at the causes of urticaria.
1, caused by infection
There are three kinds of infection: bacterial infection, viral infection and parasitic infection, and any infection may cause bad symptoms once it invades the human body. The most common viral infections are Staphylococcus aureus, hepatitis and Coxsackie virus. Parasitic infections are mostly ascaris, hookworm, schistosomiasis and so on. Bacterial infections are sinusitis, pustulosis and septicemia.
2. Physical factors
Some common stimuli in life, such as cold, heat, sunshine and friction, stimulate the human body; There is also contact between animals and plants: such as insect bites, caterpillars or moths' hair scales piercing the skin; Or skin contact with nettles, wool and other things; Moreover, strong cooling is also easy to induce urticaria. For example, if the skin is left in an alternating cold and hot environment for a long time, the skin's adaptability is not strong, which leads to urticaria.
3. Dietary effects
Incorrect diet is also one of the causes of urticaria. Some people are sensitive to certain foods or overreact to additives in food.
4. Mental factors
The appearance of urticaria is also closely related to mental factors. If a person is in a state of mental stress, anxiety or boredom for a long time, it may have an impact on endocrine. Thereby affecting the skin condition and inducing urticaria.
Pathogenesis of urticaria
Urticaria is a typical IgE-mediated type, which is caused by degranulation of mast cells mediated by IgE and the release of histamine and other inflammatory mediators. The increase of capillary permeability produces air masses. Erythema caused by vasodilation and itching caused by inflammatory mediators stimulating receptors. According to classical theory, antigen binds to specific IgE on the surface receptor of skin mast cells, which stimulates mast cells to release inflammatory mediators such as histamine. At present, the theory of IgE-mediated autoimmune diseases is the most widely studied on the pathogenesis of chronic urticaria. There is sufficient evidence to prove that most patients with urticaria have functional anti-IgE receptor antibodies and anti-IgE antibodies that can degranulate skin mast cells or basophils. Serum total IgE is higher than normal, or eosinophils or neutrophils are higher. Through the examination of skin tissue extract, it was found that histamine levels in rash and non-rash areas increased, and histamine releasing factor could activate mast cells and basophils to release histamine.
It is scientifically proved that the IgE immunoglobulin in the immune system of patients with urticaria is 1- 10 times higher than that of normal people. These higher IgE will disturb the immune system of human body, make it sensitive, and lead to urticaria, thus strengthening the immune defense function of urticaria and improving its adaptability to the environment.
How to treat urticaria?
1, away from allergens
Urticaria is a skin allergic disease, and the most fundamental prevention method is to stay away from allergens. Therefore, if you are a patient with recurrent urticaria, you need to go to the hospital for allergen testing to find out which foods you are allergic to. As long as we avoid these allergens, we can effectively prevent urticaria.
2. Drug therapy
At present, oral antihistamines are mostly used in clinic, and corticosteroids are mostly temporarily inhibited, such as oral western medicine, oral hormones, topical emulsions and ointments. Long-term or large-dose topical hormone drugs, most patients with urticaria will find that it is good to take the medicine, and if they don't take it, they will have wheal, which is more serious than before. Still can't get rid of urticaria. Therefore, it is often used to treat acute urticaria.
3. Immune antiallergic therapy
In recent years, by studying the pathogenesis of urticaria and IgE-mediated allergy, people began to intervene anti-IgE antibody immunotherapy in chronic allergic diseases such as chronic urticaria.
Xinminkang anti-allergic probiotics can participate in IgE-mediated immune allergic reaction. The combination of six patented anti-allergic strains can effectively inhibit the abnormal increase of IgE immunoglobulin, reduce the specific IgE production induced by allergens, repair the damaged immune cells in allergic reactions, and finally play a role in preventing and treating urticaria. Lactobacillus salivarius has the international patent certification for reducing serum IgE allergic antibody. After continuous supplementation for more than three months, the concentration of IgE in the body is reduced, so that allergens cannot bind with IgE antibodies in the body, and a series of allergic biochemical reactions no longer occur. Therefore, Xinmin Kang probiotics can resist IgE antibodies and regulate allergic constitution, while drugs can only relieve symptoms, but not regulate allergic constitution. The effective combination of anti-allergic drugs and anti-IgE antibody immunotherapy with anti-allergic probiotics can also produce ideal rehabilitation effect, which can eventually shorten the treatment course of urticaria and reduce the recurrence rate of urticaria.
4. Develop good living habits
Usually pay attention to a balanced diet, exercise more, keep a good mood and sleep well. These good living habits can make people's physique better, and the body's resistance will be better, so as to stay away from diseases.