However, in the process of developing and using API, many people are "difficult at the beginning, difficult in the middle and difficult at the end":
In order to search the route of drug synthesis, I searched for periodicals, papers and patent materials everywhere.
It is difficult to find information, but it takes a lot of time because of hard work and translation;
Finally, I figured out the composition details of a document, and I don't know if there are any other better methods;
I want to buy it, but I don't know which suppliers are in the market. ...
In order to solve these problems, it is suggested to use the database to query the data of raw materials. Rong Yun includes (comprehensive query of raw materials, calculation of raw materials consumption, customs import and export, synthetic routes, FDA-approved auxiliary materials, and raw material registration information of countries and regions such as CDE, DMF of the United States, MF of Japan, DMF of the Republic of Korea, CEP of the European Union).
1, inquire about the synthetic route, intermediate reagents, etc.
Under the API part of Rong Yun database, the synthetic route database contains basic information of APIs, synthetic routes, research route types, reaction steps, total yield, etc. Synthesis roadmap, reactants in each step, reaction conditions, conversion rate, etc. , and contains specific information such as reactant supplementary explanation and group description, which is beneficial to the preliminary investigation in the research and development stage and the analysis and comparison of multi-route synthesis of APIs.
Search methods such as keyword search, precise search, fuzzy search, combined search and advanced screening (and, or, or, not) can be carried out according to drug name, intermediate, reaction reagent and CAS number. , as well as synthetic routes, intermediate reagents, etc. You can check.
Query mode
Click "Name" to enter the detailed page, where you can inquire about the synthetic route, intermediates, reagents, etc.
Drug synthesis route, intermediate
Drug details