1, European Molecular Research (ENA), a public database operated by the European Molecular Biology Laboratory (EMBL), is dedicated to collecting, storing, managing and distributing different types of nucleotide sequence data and their annotation information.
2.GenBank is a DNA sequence database established by National Biotechnology Information Center (NCBI). It obtains sequence data from public resources, mainly provided directly by researchers or obtained from large-scale genome sequencing projects (Benson et al., 1998).