Microcapsule technology began in 1930s, but it developed rapidly. Up to now, more than 100 laboratories have been developing microcapsule technology.
The invention of colorless pressure-sensitive adhesive copy paper is the first successful application of microcapsule technology in business. By 198 1 year, the output of this microcapsule exceeded 5× 106 tons.
The application scope extends to medicine, pesticide, adhesive, liquid crystal and other fields.
1936165438+1October: fishermen on the Atlantic coast submitted a patent application for preparing gelatin microcapsules containing cod liver oil in liquid paraffin.
1940 10, Gelatin Products Co., Ltd. put forward a patent application for preparing double-walled microcapsules containing drugs by using concentric three-layer pointed holes. 1949 65438+1October: The Wisconsin Alumni Research Foundation put forward a patent application for microencapsulating solid particles by using the air suspension method invented by Wurster.
April 1950: Eastman Kodak Company filed a patent application for preparing mixed particles with coating (i.e. microencapsulated) emulsion and tricolor pigments for color photography.
1950165438+1October: General Deng Lupu Company filed a patent application for the preparation of alginate microcapsules with double-layer pores.
1953- 1954: NCR company put forward two patents for preparing oil-containing gelatin microcapsules and four patents for preparing microcapsule pressure-sensitive copy paper by the above method. This patent has been applied all over the world except Japan.
1March, 956: NCR company filed a patent application for microencapsulation of photoelectric materials.
In April, 1957: NCR company applied for the patent of composite microcapsule technology for color photography.
June 65438+August 0957: Moore Buslness submitted a patent application for microcapsules using spray drying technology.
1957165438+1October: General Allianz Film Company filed a patent application for microencapsulating the photographic emulsion of ethyl cellulose into mixed particles.
65438+March 0958; Xerox submitted a patent application for preparing microcapsules containing liquid imaging regulator.
65438+May 0958; NCR Company submitted a patent application for preparing heat-sensitive adhesive by microcapsule technology.
June 1958: NCR Company filed a patent application for the preparation method of oil-containing polystyrene microcapsules. In this method, monomers are used and an in-situ polymerization process is applied.
1958 65438+February: Upjohn filed nearly 20 patent applications. They are all microencapsulation methods of "emulsion". In these patents, some improved the coagulation method of NC R and applied thickener. Some people put forward the method of phase separation in organic solvent system; Some people have proposed methods to solidify gelatin microcapsules ... some similar methods. 1963, all these patents were transferred to NCR company.