Li Shizhen typhoid fever patent

It's like asking Qin Qiong or Guan Gong who is better at martial arts. Hua tuo once suggested splitting Cao Cao's head with a knife and axe to treat the disease. Hua tuo should have made great achievements in clinical medicine.

Bian Que invented anesthetics and made great achievements in pharmacy.

Sun Simiao and Li Shizhen wrote "A Thousand Daughters' Prescriptions" and "Compendium of Materia Medica" respectively, and they have made great achievements in medical theory.

As for Zhang Zhongjing (I don't know him very well), he is also a famous doctor.

The famous doctors mentioned above have different specialties in different times. It is difficult to put them together and compare their medical skills.