Question 1: How to eradicate Helicobacter pylori (HP positive)? Once infected with Helicobacter pylori, it is difficult to completely eliminate it even with antibiotic treatment, and most people will carry the bacteria for life. Helicobacter pylori mainly exists in the oral cavity and gastrointestinal tract, and many people do not know that they are infected. If you often feel stomach pain (which is easy to occur during seasonal and climate changes), bloating, indigestion, bad breath, acid reflux, belching, etc., you are likely to be infected by Helicobacter pylori, and you should go to the hospital for an Helicobacter pylori test as soon as possible.
Dr. Xiao said that Helicobacter pylori is extremely contagious. It enters the human body through infected food and water, "settles" and reproduces on the gastric mucosa, first causing gastritis and then developing into gastritis. Gastric ulcer, gastric cancer. It is generally transmitted through three ways: first, bowls and chopsticks. Boiling bowls and chopsticks for 10-15 minutes every day can kill most Helicobacter pylori; second, contact with the bed. People with Helicobacter pylori can contaminate bedding through saliva and breathing. , pillows, causing infection among family members, bedding and pillows should be disinfected and changed frequently; third, pets such as cats and dogs are easy to carry Helicobacter pylori, and close contact with pets should be avoided.
Drug treatment for Helicobacter pylori infection usually involves taking 2 to 3 antibiotics plus proton pump inhibitors, commonly known as triple therapy. However, it is easy to develop resistance to Helicobacter pylori and cause side effects of destroying the probiotic flora in the digestive tract. Middle-aged and elderly friends can also prevent and treat Helicobacter pylori by doing three things in their daily lives. Clean the mouth. The mouth is an important source of infection for Helicobacter pylori. Taking antibiotics such as metronidazole generally has a killing effect on Helicobacter pylori in the stomach, but it is often ineffective against Helicobacter pylori in the mouth. This can easily cause the bacteria in the mouth to be infected. Enters the gastrointestinal tract causing recurrent episodes of infection. Therefore, to prevent gastrointestinal infections, we must first completely remove Helicobacter pylori from the oral cavity.
Helicobacter pylori is also present in large amounts in dental plaque. When the body's resistance decreases, Helicobacter pylori swallowed into the stomach with saliva or food will cause trouble, leading to the onset of gastric disease. Helicobacter pylori in the mouth can also cause bad breath. To prevent and treat Helicobacter pylori, you must pay attention to oral hygiene, change your toothbrush every month, and insist on rinsing your mouth and brushing your teeth after each meal to prevent the formation of tartar and plaque. In addition, you can also make your own medicated toothpaste to kill Helicobacter pylori. Grind 20 grams of mint leaves (available in pharmacies) into powder, squeeze out 60 grams of toothpaste and put it in a clean container. Add the mint powder and mix evenly. Use it to brush your teeth every day. , used continuously for 30 days, can effectively kill Helicobacter pylori parasitizing on dental plaque.
Middle-aged and elderly friends who wear dentures should pay more attention to keeping their mouths clean. Before going to bed every night, take out the dentures and soak them in rice washing water. After getting up the next day, take out the dentures and brush them with soft bristles in clean water. Rinse it clean and put it in your mouth. Rice washing water contains a variety of biological enzymes, which have decontamination functions and can avoid the formation of dental plaque. Moreover, rice washing water has no corrosive effect on dentures. Food sterilization
Cabbage has antibiotic effects and can kill a variety of bacteria including Helicobacter pylori. Drinking the juice of 1/4 cabbage every day can reduce the symptoms of gastric ulcers and ulcers after 3 weeks. Abdominal pain caused by duodenal ulcers and aids in the healing of both ulcers. Cabbage also contains a chemical similar to gastrointestinal ketone, which can cause gastrointestinal cells to secrete mucus to form a barrier to isolate gastric acid and protect the stomach from damage. The fresher the cabbage, the better the anti-ulcer effect.
Purple-skinned garlic can inhibit the reproduction of Helicobacter pylori. Fresh garlic is pungent and has strong bactericidal power. Consistently eat one piece of raw purple-skinned garlic with meals every day, and the antibacterial effect will be apparent after two weeks.
Honey can inhibit all Helicobacter pylori when the experimental concentration is 20~/6; half of Helicobacter pylori can be inhibited when the concentration is 10%. Honey mainly inhibits Helicobacter pylori through osmosis; therefore, honey should be drank after meals to extend the time it stays on the gastric mucosa. Put 30 ml of honey in a bowl, stir with chopsticks until foamy, add 120 ml of warm water, mix well, and drink slowly.
Clove is a common Chinese herbal medicine with strong anti-Helicobacter pylori effect. Soak 6 grams of clove in water every day for two weeks.
Drink tea with cold boiled water. Tea contains a large amount of tea polyphenols, which has a strong effect on killing Helicobacter pylori. However, tea also contains caffeine, which will promote increased gastric acid secretion, which is harmful to the gastrointestinal tract. Tract ulcers are unfavorable. Making tea with cold boiled water can reduce the dissolution of caffeine and will not cause gastric acid secretion. Soak 5 grams of tea leaves in cold boiled water for half an hour before drinking.
Broccoli Fresh broccoli contains large amounts of sulforaphane, which helps fight Helicobacter pylori. Studies have found that people who eat broccoli every day can reduce the level of Helicobacter pylori antigen in their feces by more than 40%. Cut 200 grams of broccoli into small pieces, blanch it quickly in boiling water, and serve cold. Reduce gastric acid
Helicobacter pylori is suitable...gt;gt;
Question 2: How to treat Helicobacter pylori? At present, the following options are commonly used to cure Helicobacter pylori:
1. Two types of proton pump inhibitors (English abbreviation "PPI", commercially available such as omeprazole, lansoprazole, etc.) Antibiotics: PPI standard dosage of amoxicillin 1.0g and clarithromycin 0.5g, both twice a day, one week is one course of treatment; PPI standard dosage amoxicillin 1.0g and metronidazole 0.4g, both twice a day, one week is one course of treatment Course of treatment: PPI standard dosage of metronidazole 0.4g and clarithromycin 0.25g, twice a day, one week is a course of treatment.
2. Bismuth agent: Livzon Gastric Triple: It is composed of bismuth agent (Livzon Dele) + two antibiotics. It is currently a very effective drug for the eradication of Helicobacter pylori. It can be taken continuously in one course of treatment. Within seven days, the radical cure rate reaches over 90%; bismuth agent and two antibiotics: bismuth agent (Livzon Dela is recommended) standard dose amoxicillin 0.5g and metronidazole 0.4g, both twice a day, 2 weeks as a course of treatment; bismuth agent (Livzon Dela is recommended) standard dose tetracycline 0.5g and metronidazole 0.4g, twice a day, 2 weeks as a course of treatment; bismuth (Livzon Dela is recommended) standard dose clarithromycin 0.25g metronidazole 0.4g, twice a day, 2 weeks as a course of treatment.
3. Other options: Ranitidine bismuth citrate (RBC) 0.4g replaces the PPI in recommended option 1. H2-receptor antagonist H2-RA) or PPI recommended regimen 2 consists of quadruple therapy, with a course of one week. Metronidazole 0.4g in the protocol can be replaced with tinidazole 0.5g.
It is very necessary to prevent Helicobacter pylori infection. Pay attention to personal hygiene: such as gargling after each meal, sharing meals, washing vegetables and fruits, etc. to minimize the chance of infection.
Question 3: How to cure Helicobacter pylori infection? Drug treatment of Helicobacter pylori infection usually involves taking 2 to 3 antibiotics plus a proton pump inhibitor, commonly known as triple therapy. However, it is easy to develop resistance to Helicobacter pylori and cause side effects of destroying the probiotic flora in the digestive tract. Middle-aged and elderly friends can also prevent and treat Helicobacter pylori by doing three things in their daily lives. Clean the mouth. The mouth is an important source of infection for Helicobacter pylori. Taking antibiotics such as metronidazole generally has a killing effect on Helicobacter pylori in the stomach, but it is often ineffective against Helicobacter pylori in the mouth. This can easily cause the bacteria in the mouth to be infected. Enters the gastrointestinal tract causing recurrent episodes of infection. Therefore, to prevent gastrointestinal infections, we must first completely remove Helicobacter pylori from the oral cavity.
Question 4: Has Helicobacter pylori been completely eradicated from my body? Condition analysis:
Helicobacter pylori is only one of the normal flora in the human body, so it cannot be completely eradicated. It is not pathogenic under normal circumstances.
Guidance:
Generally, after 1 to 2 weeks of regular anti-H. pylori treatment, most infected people can be cured. Helicobacter pylori infection can be cured. The general treatment principle is to give priority to antibiotics. For chronic Radical treatment is also recommended for patients with atrophic gastritis and dyspeptic symptoms who have poor response to conventional treatments, patients with reflux esophagitis who need long-term acid suppression treatment, and those who need long-term use of non-steroidal anti-inflammatory and analgesic drugs. For infected patients who do not meet these conditions , the doctor will explain the pros and cons to the patient in detail before making a choice.
Lifestyle care:
Spicy and hard food, hard food, moldy food, coffee, barbecue, hot pot, and cigarettes are taboo Alcohol, this disease is mainly about maintenance. To cure gastric ulcer, it needs a relatively difficult and long-lasting process. In addition to cooperating with medical staff for active treatment, patients should also do good self-care. Mainly follow the traditional Chinese medicine's "three-point treatment, seven-point treatment" for gastrointestinal diseases. The guiding ideology of "separate nutrition"
Hello! As long as it is treated correctly, it can be cured. Helicobacter pylori is an important cause of gastric disease. Generally, conventional treatment methods are difficult to achieve and can only alleviate the condition, but cannot Solve the fundamental problem and it is easy to relapse. The traditional Chinese medicine of the motherland has a very unique treatment method. It is recommended that you use the traditional Chinese medicine black vitriol, black dates, walnut kernels, gardenia, angelica, amomum villosum, magnolia officinalis, trigonellae, pangolin, cunqu. , malt, upper nail, lower nail, safflower, Hainan Shen, iron gall powder, propolis, honey, beeswax treatment, the effect is accurate, many patients do not relapse after cure; these traditional Chinese medicine formulas are unique, can directly attack the lesions and completely clear the pylorus Helicobacter increases the gastric mucosal barrier, eliminates the root cause of the disease, and achieves complete cure.
You can buy these drugs at local pharmacies. I hope you receive correct treatment and recover soon!
nHello Helicobacter pylori is the main cause of gastritis. The eradication rate is 78. Thank you
Condition analysis:
You can choose drugs that can treat Helicobacter pylori for treatment
Guidance:
It can be completely cured ~ but you will not acquire immunity. If you come into contact with people who carry Helicobacter pylori, eat together, etc., you will still be infected with Helicobacter pylori
Condition analysis:
Helicobacter pylori is a unipolar, multi-flagellated bacterium with a blunt end and a spiral curve. It is 2.5 to 4.0 μm long and 0.5 to 1.0 μm wide. Gram Staining is negative and dynamic. The surface of gastric mucosal epithelial cells often appears in a typical spiral or arc shape. When grown on solid media, in addition to the typical morphology, rod-shaped or spherical shapes may sometimes appear.
Under normal circumstances, the gastric wall has a series of complete self-protection mechanisms (gastric acid, secretion function of protease, protective effect of insoluble and soluble mucus layer, regular exercise, etc.), which can resist the attack of thousands of microorganisms introduced through the mouth. Invasion. Since the discovery of Helicobacter pylori on the surface of gastric mucosal epithelial cells, it has been realized that Helicobacter pylori is almost the only culprit that can break through this natural barrier. Helicobacter pylori infection has significantly increased the occurrence of duodenal and gastric ulcers. The risk. About 1/6 of people infected with Helicobacter pylori may develop peptic ulcer disease. Treatment of Helicobacter pylori infection can accelerate the healing of ulcers and greatly reduce the recurrence rate of ulcers. Instead of using acid suppressants, use anti-Helicobacter pylori drugs alone. Treatment, has also been shown to be effective in curing gastric and duodenal ulcers. Helicobacter pylori infection has been linked to some causes of ulcer disease.
Guidance:
Treatment The selection principles of the plan are: ① Use combined medication; ② The eradication rate of Helicobacter pylori is >80%, preferably above 90%; ③ There are no obvious side effects and the patient has good tolerance; ④ The patient can afford it economically. Determine the Helicobacter pylori eradication rate The therapeutic effect of Helicobacter infection should be based on the eradication rate of Helicobacter pylori rather than on the eradication rate of Helicobacter pylori.
Eradication rate. Eradication refers to the absence of bacterial growth confirmed by bacteriology, histopathology or isotope tracing methods at least one month after treatment is terminated.
Oral hygiene should be paid attention to before eradication of Helicobacter pylori. You can change your dental appliances first, and use mouthwash and antibacterial toothpaste for a period of time to repair oral problems such as tooth decay, tartar, calculus, etc.
Currently, anti-Helicobacter pylori drugs commonly used at home and abroad include amoxicillin, Nitrazole, clarithromycin, tetracycline, doxycycline, furazolidone, organic colloidal bismuth (de-nol, etc.), Weidele (Weisure), Ledewei, Sipi's powder and Weisuping. Patients with ulcer disease still have Proton pump inhibitors or H2 receptor antagonists plus two antibiotics can be appropriately combined, or proton pump inhibitors (such as omeprazole) plus...gt; gt;
Question 5: How to treat Helicobacter pylori Helicobacter pylori infection is currently mainly treated with anti-Helicobacter pylori drugs.
Although Helicobacter pylori is sensitive to many antibacterial drugs in vitro, the use of drugs in vivo is not so satisfactory. This is because Helicobacter pylori mainly lives under the mucus
detector
layer and on the surface of gastric epithelial cells. The injection route has no effect on it, and the oral route is due to the acid environment of the stomach. The barrier of the mucus layer and the continuous emptying of the stomach greatly limit the efficacy of the medicine. In addition, long-term use of some drugs is prone to serious side effects or drug-resistant strains and other problems. Therefore, diseases such as acute and chronic gastritis and peptic ulcer caused by Helicobacter pylori infection may appear to be easy to treat, but in fact the results are not always ideal. What's more, there is currently a lack of suitable animal models of Helicobacter pylori infection that can help develop effective treatment plans.
Therefore, the current treatment plans are almost entirely based on clinical experience and have great limitations (due to differences in regions and populations). Generally speaking, the use of a single antibacterial drug is currently not recommended because its cure rate is low, generally 80, preferably above 90;
③No obvious side effects, and the patient tolerates it well;
④The patient’s financial affordability.
The treatment effect of Helicobacter pylori infection should be judged based on the eradication rate of Helicobacter pylori, rather than the clearance rate. Eradication is defined as the absence of bacterial growth confirmed by bacteriological, histopathological, or isotope tracing methods at least one month after discontinuation of treatment.
Currently, the commonly used anti-Helicobacter pylori drugs at home and abroad include: Weifuchun tablets, amoxicillin, metronidazole, clarithromycin, tetracycline, doxycycline, furazolidone, organic colloidal bismuth ( de-nol, etc.), Weidele (Weisure), Ledewei, Sipi's powder and Weishuping. Patients with ulcers can still use a combination of proton pump inhibitors or H2 receptor antagonists plus two antibiotics, or proton pump inhibitors (such as omeprazole) plus one antibiotic.
Medication regimen:
Omeprazole (pantoprazole or rabeprazole) clarithromycin (levofloxacin) amoxicillin (metronidazole)
Treatment time: The course of treatment usually lasts two weeks. Due to the widespread use of antibacterial regimens for the treatment of Helicobacter pylori infection, the problem of drug resistance is likely to amplify. Therefore, future research on alternative treatment or prevention strategies, such as vaccine prevention or immunotherapy, is worthy of attention.
Helicobacter pylori
Prevention strategies:
Oral hygiene should be paid attention to before eradication of Helicobacter pylori. Use mouthwash and antibacterial toothpaste for a period of time to repair oral problems such as tooth decay, tartar, tartar, etc. You can replace the dental appliances first. Do not put the dental appliances in the bathroom, but place them in a place where the sun can shine. Bathrooms without windows should be regularly sterilized and disinfected by ultraviolet light for more than 30 minutes. Do not mix mouth cups, water cups, and stainless steel thermos cups, and frequently It is necessary to steam and sterilize, especially during drug treatment, and sterilize bowls and chopsticks separately for meals.
1. Change the toothbrush, pasteurize the patient's cup washing utensils on time, and use mouthwash in the morning and evening.
Mouthwash should have bactericidal effect, that is, its formula should be chemical agents, such as the main ingredients are thymol, thymol or compound tinidazole liquid. Mouthwash with Chinese herbal ingredients is ineffective.
2. It is contagious and highly contagious. When someone at home is infected, meals must be divided and a household disinfection cabinet must be used to disinfect tableware after each meal every day.
3. Most patients do not do the first step well, that is, they do not use medical mouthwash, they do not sterilize their personal toiletries, and they just blindly take "triple" drugs. Such treatment will only temporarily improve them. , the recurrence rate is high after drug withdrawal. It may not fully recover for a year, two years or even longer, and eventually develop into gastritis or atrophic gastritis. Patients who do well in the first step can be cured within two weeks.
4. The best effect is to take antacid drugs on an empty stomach before going to bed. Choose between omeprazole, rabeprazole, and lansoprazole.
5. Be sure to use antibacterial drugs. Do not eat sour foods or drink yogurt during the medication, otherwise the treatment will be in vain.
6. Helicobacter pylori drug-resistant treatment
Proton pump inhibitor or H2 receptor antagonist bismuth amoxicillin levofloxacin for 10-14 days, or proton pump inhibitor Or the H2 receptor antagonist bismuth amoxicillin and levofloxacin, which should be administered for 5-7 days, followed by the proton pump inhibitor or the H2 receptor antagonist bismuth amoxicillin and levofloxacin, which should be administered for 5-7 days (i.e., antibiotics are administered sequentially). The eradication rate of Helicobacter pylori can reach about 90%. ...gt;gt;
Question 6: How to treat Helicobacter pylori infection? Introduction to triple therapy:
Gastric triple therapy refers to a treatment method of two antibiotics, colloidal bismuth or proton pump inhibitor (PPI). Generally speaking, the duration of triple medication is one to two weeks. In addition, gastric mucosal protective agents, gastric emptying-promoting drugs, anticholinergic drugs, etc. can also be used appropriately according to the condition.
Advantages of triple therapy:
Compared with single antibiotic therapy and dual therapy, triple therapy has the advantage of high eradication rate. In previous years, when Helicobacter pylori resistance was not as common as it is today, the eradication rate of triple therapy could reach 85-95%.
Problems with triple therapy:
The first is the problem of side effects. Almost all commonly used antibiotics have certain side effects. For example, metronidazole, the two most commonly used antibiotics in Sanlian, can cause nausea and burr tongue; amoxicillin and erythromycin can cause diarrhea, nausea, glossitis, allergic urticaria, rash, and drug fever.
Then, the most important problem that has troubled clinicians in recent years is the increasing drug resistance of Helicobacter pylori. Data released by the recent 6th Helicobacter pylori Clinical Diagnosis and Treatment Forum show that due to the increase in drug resistance, the eradication rate of Helicobacter pylori in traditional triple therapy is declining year by year. The eradication rate of triple therapy in some areas has dropped to about 65%.
Helicobacter pylori quadruple therapy
Introduction to quadruple therapy:
Quadruple therapy refers to a treatment plan of colloidal bismuth and three antibiotics. Commonly used drug combinations and dosages are as follows:
1. Bismuth potassium citrate 240 mg + amoxicillin 750 mg + metronidazole 400 mg Omeprazole 20 mg
2. Bismuth citrate Potassium 240 mg + erythromycin 500 mg + metronidazole 400 mg, omeprazole 20 mg
3. Bismuth potassium citrate 240 mg + tetracycline 500 mg + metronidazole 400 mg, omeprazole 20 mg
A course of treatment lasts from 7 to 14 days. After the first course of treatment, you should continue to take bismuth potassium citrate alone for 6 weeks. The dosage and usage are the same as before. Note that a skin test is required for amoxicillin (amoxicillin is a penicillin-type spectrum antibiotic.)
Advantages of quadruple therapy:
The remission rate and eradication rate of quadruple therapy in treating Helicobacter pylori infection are higher than those of triple therapy, with the remission rate being more than ten percentage points higher. , the eradication rate is several percentage points higher.
The drug resistance rate of quadruple therapy is slightly lower than that of triple therapy. It is currently the most commonly used first-line treatment for Helicobacter pylori in clinical practice, and is the second-line therapy after failure of triple therapy.
Problems with quadruple therapy:
Due to the addition of an antibiotic, quadruple therapy not only has a higher remission and eradication rate than triple therapy, but also has a higher incidence of side effects than triple therapy 5 The percentage effect is about 30. Although the drug resistance rate is temporarily lower than that of Sanlian, it is getting higher and higher. Therefore, the eradication rate of Helicobacter pylori with quadruple therapy is also decreasing year by year. The latest data shows that the eradication rate of quadruple therapy has dropped to about 70%.
Research progress of quadruple therapy:
Like triple therapy, the latest research shows that if antibiotics with lower resistance rates such as furazolidone are used instead of antibiotics with resistance such as metronidazole If antibiotics with higher rates are used, the eradication rate of the quadruple drug can also be improved. In addition, studies have also shown that extending the course of quadruple therapy can also improve the eradication rate of Helicobacter pylori.
Helicobacter pylori probiotic therapy
As the eradication rate of Helicobacter pylori with triple and quadruple combinations decreases year by year, the 6th National Clinical Forum on Helicobacter pylori Infection and Digestive Diseases, and At the roundtable meeting on new pathways for the treatment of Helicobacter pylori, probiotic therapy for Helicobacter pylori received widespread attention and recognition.
Du Yiqi, Hu Fulian and other experts gave a detailed introduction to Helicobacter pylori probiotic therapy:
Introduction to probiotic therapy:
Probiotic therapy refers to, Add probiotic preparations to the traditional triple or quadruple combination, or directly use Weiyueke probiotic preparations to eradicate Helicobacter pylori.
Advantages of probiotic therapy:
Current domestic and foreign clinical studies have shown that probiotic therapy can increase the eradication rate of triple and quadruple drugs by 10-20%, and can increase the eradication rate of triple and quadruple drugs. The associated adverse reactions are reduced by more than 20%.
Problems with probiotic therapy:
The main question at present is whether probiotics are more effective when used in combination with triple or quadruple combinations, or whether they are used alone, which still needs to be verified.
Helicobacter pylori post-healing care
1. If you want to change the way you eat, you should choose separate meals or use public chopsticks.
2. Drink boiled water instead of raw water, eat cooked food instead of raw food, and drink milk after sterilization.
3. Experiments have shown that patients with ulcers may also be at risk of spreading the disease when they kiss others, so we should be vigilant.
4. Develop good hygiene habits and wash hands before meals and after using the toilet. Tableware that is frequently used must also be strictly disinfected.
5. Do not store toothpaste and other cleaning supplies in the sanitary area...gt;gt;