After the U.S. patent passes the reply to the first examination opinion, if the examiner still disagrees with the applicant’s opinion, a Final Office Action will be issued to reject the applicant’s defense, but rejection does not mean that When the case is terminated, the applicant can use the following channels: (1) Modify the scope of the patent in accordance with the examiner's opinions; (2) Appeal to the Appeal Board; (3) RCE (application for continuation of examination) to obtain the opportunity to continue the defense.