In domestic similar disciplines, this direction has obvious advantages in the separation, purification and characterization, large-scale preparation and production of protein. However, compared with the top research institutions in protein, the research on basic theory needs to be strengthened.
2. pharmaceutical biotechnology direction: The characteristic of this research direction is to study the intrinsic dynamics and macro-process dynamics of key biochemical products and biochemical processes, and to separate and purify related biochemical products, so as to realize engineering amplification and process optimization. This research direction includes: optimization of microbial reaction process, development of new bioreactor and separation and purification of related new biochemical products.
(1) Study on the characteristics and optimization of microbial process
This direction is mainly engaged in the study of intrinsic dynamics and process dynamics of microbial reaction, and carries out the optimization of biological reaction process and the optimal design and control of related reactors, so as to realize the efficient operation of the target biochemical reaction process.
(2) Study on new environmental bioreactor
Aiming at the anaerobic biodegradation process of high-concentration organic wastewater and low-concentration domestic sewage, the characteristics of anaerobic bioreactor were studied emphatically, and the optimal control measures of bioreactor were discussed from the engineering point of view and microorganism point of view respectively, and practical related wastewater biological treatment technologies were developed.
(3) New biochemical separation technology
Biochemical separation engineering plays an important role in biotechnology. This direction mainly studies the new technology and process of biochemical separation according to the characteristics of biochemical reaction products. Emphasis is placed on membrane separation, chromatographic separation, ion exchange separation and supercritical fluid extraction.
(4) In this research direction, pharmacogenomics research led by Professor Hong Wenrong focuses on strain screening, strain improvement, microbial pharmacogenomics, resistance gene cloning, gene cluster cloning of antibiotic biosynthesis, gene knockout, gene blocking, gene replacement, cell engineering breeding, secondary metabolite metabolism network regulation and fermentation process optimization, antibiotic separation, extraction and purification, and antibiotic industrialization research. Among them, tobramycin-producing bacteria have been industrialized through quality improvement and optimization, and their technical indicators have reached the leading level in China. The gene cluster cloning of micromonospora eneuvensis, a sisomicin-producing strain with different genetic traits, has made a breakthrough, applied for a patent and won the third prize of provincial scientific and technological progress, filling the gap in this research field in China. Other varieties studied include kanamycin, gentamicin, tobramycin, micronomicin, sisomicin, ribomycin, chlortetracycline, oxytetracycline, tetracycline, rifamycin, erythromycin, cyclosporine A, cephalosporins, clavulanic acid, vancomycin and cyclosporine A, etc. Most of its production technical indicators have been higher than the level of industrialization.
3. direction of food biochemistry: on the basis of a solid science of biochemistry, carry out research on traditional foods. Specifically, the current research directions include 1. Research on food analysis methods 2. Research on protein traditional foods 3. Research on fermented traditional foods. Introducing the latest analytical methods is the prerequisite for the breakthrough of traditional food research. The new methods developed by this discipline to analyze the composition and function of food by chromatography and capillary electrophoresis effectively reveal the composition and mechanism of traditional food, and reflect the in-depth research work and the advantages in means. In the general trend of imitating and tracking the international ready-made food science and technology, this discipline insists on carrying out the research on China traditional food, regarding it as the sacred duty to build the core competitiveness of China food industry and the foundation for this discipline to stand on its own feet in the forest of international food science and technology.
In this direction, the biochemical basis for the coolness of yellow rice wine, Fuzhou Rouyan, bean curd and China fruits was studied, which provided a new perspective for people to understand these important traditional foods at the molecular level and laid a foundation for the industrialization and internationalization of related foods. These efforts have been supported by domestic and international food industries, and a brand-new situation of cooperation between industry and university has emerged, which is entering a fruitful harvest season.
another distinctive feature of this direction is that it has a successful entrepreneurial experience that is rare in academic circles, has a strong industrialization ability, and has a natural advantage in communication with the food industry, realizing high-level technical cooperation and exchanges with domestic and even international food enterprises. At present, it has established R&D institutions with Shengnong Group, Crayon Shinchan, Fumajituan and other three major food enterprises in Fujian Province. The cooperative research of Nestle, Danone, Effen, Japan Ajisen and other companies has begun. This subject is becoming a technical power source to promote the development of food industry in our province.
the outstanding weakness of this discipline lies in the lack of communication skills in seeking government resources to support the forward-looking research carried out by the discipline.
4. direction of applied ecology:
(1) to develop a brand-new inland culture technology of marine fish, which has been successful in the culture of Penaeus vannamei and grouper, and is now being promoted in the mainland. This technology can not only avoid the potential risks caused by the changeable and harsh climate in the sea area, but also make full use of land resources, artificially improve ecological conditions, shorten the growth cycle and reduce production costs.
(2) The new technology of freshwater fish ecological culture has been successfully used in turtle and tilapia culture. Turtle culture has been extended to Fujian, Zhejiang, Guangdong, Jiangxi, Hainan and other provinces, and achieved great economic and social benefits. Associate Professor Yuan Chonggui, an academic leader, was called "Dr. Turtle" by farmers.