Japan, on the other hand, opened the production of classical Chinese medicine a long time ago. The Japanese summarized the clinical experience of China for thousands of years, and made some clinical verification by scientific means, so as to select some classic prescriptions for mass production. In this way, China's classic prescription shines brilliantly in Japan, earning a lot of money for Japanese pharmaceutical companies. For example, China's ancient prescription "Liushen Pill" was developed after Japanese transformation. Once popular all over the world, it was known as a "life-saving medicine" with annual sales exceeding $6,543.8 billion. Japanese traditional Chinese medicine "Lu Zheng Pill" has also been sold back to China. Among the countries applying for patents of traditional Chinese medicine in China, Japan, South Korea, the United States and Germany are the most enthusiastic.