Is there a way to cure the 2007 layer bird flu?

Tamiflu is the only drug currently known to have a therapeutic effect on avian influenza.

3R,4R,5S)-4-acetylamino-5-amino-3(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester

INN common name Oseltamivir

CADN common name Oseltamivir

Molecular formula C16H28N2O4

Molecular weight 312.4 g/mol

Au Setasvir () is a specific inhibitor that acts on neuraminidase. It inhibits the action of neuraminidase and can inhibit mature influenza viruses from leaving host cells, thus inhibiting the spread of influenza viruses in the human body. Spread to treat influenza. Oseltamivir is a successful case of rational drug design based on structure. In the development process of this drug, computer-aided drug design methods were widely used. According to the three-dimensional structure of the target enzyme, an efficient, low-toxic and specific drug was designed in a targeted manner. A potent neuraminidase inhibitor.

Roche Pharmaceuticals Co., Ltd. is the patent holder of oseltamivir. They currently produce oseltamivir phosphate capsules (trade name in mainland China - {Tamiflu}-, Hong Kong translation - {Tamiflu}-, translated as -{Influenza}- in Taiwan) is the only oseltamivir preparation on the market. In October 2005, due to the spread of avian influenza around the world, there was a rush to buy Tamiflu. Roche was also widely criticized for its refusal to open up the patent rights of oseltamivir and restricting the sales of Tamiflu. Condemn

Oseltamivir specifically inhibits neuraminidase and has therapeutic and preventive effects on influenza caused by subtypes of influenza viruses such as H5N1 and H9N2. According to information published on the Roche website, patients who take oseltamivir within 24 hours of the onset of illness will shorten the course of the disease by 30%-40% and the condition will be relieved by 25%. As a preventive drug, oseltamivir is effective against influenza viruses. The protection rate for those exposed is between 80% and 90%.

There are two dosage forms of oseltamivir currently on the market, one is capsule and the other is oral suspension. The specification of the capsule is 75mg, the suspension solvent is water, and the specification is 12mg/mL.

Manufacturer's recommended dosage for influenza treatment is 75 mg twice daily for adults and adolescents (13 years and older) for 5 days starting two days after symptoms begin. . There is no recommended dose for infants under one year of age. For influenza prevention, adults and teenagers (over 13 years old) take 75mg daily for 7 days to get 6 weeks of protection. The longer you take it, the greater the cumulative dose and the longer you get protection.