Engaged in respiratory medicine and respiratory critical care medicine, the main research direction is the molecular pathogenesis and treatment of lung injury and lung cancer. Received funding for 28 scientific research projects, including leading key projects of the National Natural Science Foundation of China and participating in key projects of the US NIH. It has published more than 340 papers, including more than 50 papers in SCI-indexed journals, with a cumulative impact factor of more than 210 points. He is the editor-in-chief of "Diagnosis and Differential Diagnostics of Respiratory Diseases", "Acute Respiratory Distress Syndrome", "Essentials for Diagnosis and Treatment of Respiratory Diseases and Quality Control Requirements" and "Nuclear Medicine Examination of Respiratory Diseases", and has participated in the compilation of many monographs and textbooks. He was the first in the world to propose the application of wireless sensing technology to monitor respiratory function and successfully developed a prototype. In 2009, ATS Journal (ATS NEWS | VOL.35 NO.7/8,) published a special report on this issue and is currently researching it. Comprehensive application of wireless sensing technology in cardiopulmonary function monitoring. In addition, he also took the lead in applying biophysical technology to develop a dynamic real-time blood gas analyzer, and obtained "a double-stranded RNA and its use" (Patent No.: ZL03115489. 1) and "in vivo real-time light-sensitive blood sodium ion sensor and its preparation method" and other invention patents (patent number: ZL20051 0110731.2). He won the second prize of the National Science and Technology Progress Award in 2009: "Research on the Pathogenesis and Treatment of Respiratory Failure" (the second person to complete it); the first prize of the Chinese Medicine Award in 2006: "Research on the Clinical Application of Respiratory Support Technology" (the third person to complete it) ; In 2005 and 2009, he won the first prize and the gold medal (the first completer) in the Shanghai Outstanding Invention Selection Competition respectively; as well as the "Third Prize of the National Medical and Health Science and Technology Progress Award" twice and many other awards.