What is the pharmacological activity, efficacy, function and clinical application of konjac?

1, influence on ganglion

Heliotrine was found to have ganglion blocking effect. In vitro experiments show that100μ g ml-1heliotrine can significantly reduce the excitability (spasmodic response) of ganglion caused by nicotine, and its LP30 is 3 times stronger than that of known nerve blocker diazepam/kloc-0. Moreover, Heliotrine has neither central nervous system activity nor central muscle block effect, and has no effect on improving spasm caused by acetylcholine and barium chloride.

2. Antibacterial and antitumor effects

At present, there are many studies on rutanine. Pharmacological studies show that it has significant activity on experimental tumor system walker-256 system, strong inhibitory activity on Candida crescent, and the greatest inhibitory effect on Candida tropicalis. Positive.

3. Anti-inflammatory and analgesic effects

The water-soluble extract of tongue coating (Vahb) was used to study xylene-induced ear swelling and capillary permeability in mice. The results showed that the purine alkaloids in the extract had anti-inflammatory and analgesic effects.

4. Efficacy and function of cloves

This genus is rich in PA and has unique pharmacological and toxicological effects. On the one hand, as a traditional folk medicine in southwest China, it is widely used to treat malaria, hepatitis, dysentery, dysuria, abnormal leucorrhea, tuberculosis and cough, and externally used to treat traumatic bleeding, fracture and joint dislocation. In clinical use, it has achieved good curative effect; On the other hand, because some PAs components have hepatotoxicity and other toxic effects, countries have strictly restricted their content in food.

5. Treatment of prostate diseases

According to a patent report in China, Zhao used Daoguan and its extract to treat prostate diseases and sexual dysfunction caused by prostate diseases. Some physiological functions, improve human defense ability and quality of life.

6. Treatment of anorectal diseases

Lily of Liliaceae or its extract can be used for treating anorectal diseases, such as hemorrhoids, constipation and proctoptosis. After being used by nearly 100 patients, the effective rate is about 90%. Such as anorectal diseases, provides a new choice.

7. Treat alopecia

Raw materials, processed products and extracts of Liliaceae plants are used as effective components. ? 85%, especially for androgenetic alopecia. After taking the medicine for 30 days, the hair loss stopped. After 2 to 3 months of use, atrophied hair follicles began to repair, and bald people grew new hair. The bald area is gradually covered by new hair, and the growth and metabolism of hair gradually return to normal. State.