Surfactant solubilization

This is some information I checked: the solubilization experiment of Ginkgo biloba extract was carried out with the least toxic nonionic surfactant as solubilizing agent, and the experimental results showed that the solubilization effect was Tween-80 >; Twain-20 >: PEG600, Span series, ethylene glycol polymer, no solubilization. Each gram of Tween -80 can solubilize 2 grams of Ginkgo biloba extract, and the solubility of Ginkgo biloba extract in aqueous solution is only 0.005 grams/gram, and the solubility of Ginkgo biloba extract can be increased to 0.05 grams after adding Tween -80. According to the kinetic and thermodynamic calculation of the decomposition reaction of effective components, the liquid preparation of Ginkgo biloba extract with Tween -80 as solubilizing agent can keep the mass fraction of effective components above 90% at room temperature (25℃) for 479d d.

Patent technology 148 item

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