Does the questioner want to ask "What's wrong with the joint pain in the hands and feet of Pegbin"? side effect. According to the information on Zhihu.com, Pegbin has side effects. If the drug is injected for a long time, the muscle tissue will be affected, resulting in muscle soreness, including damage to soft tissues such as joints. Pegbin (common name: polyethylene glycol) Interferon α-2b injection) is a national Class 1 new drug independently developed by Xiamen Tebao Bioengineering Co., Ltd. that is effective in treating viral hepatitis.