Absorbability; In 1960 AD, Americans invented chemically synthesized absorbable sutures; including PGA, PLA, artificially synthesized absorbable sutures, the raw materials are: artificial metabolites (glycolic acid, lactic acid) Polymerized, the production process is spinning, stretching, coating and other processes, and the absorption method is hydrolysis; it is easy to operate and the absorption time is predictable; its absorption time is closely related to the moisture content of the suture, and the higher the moisture content, the better. The absorption time is short, and the low water content means the absorption time is long, so it has higher requirements on the production and storage environment; until now, because the main ingredients are chemical substances and contain chemical coatings, there is still incomplete absorption and mild tissue rejection. reaction.
The United States began to implement a suture approval system in 1970; the suture patent protection period is 14 years.