"Biyanling nasal drops" is designed and developed according to the pathogenic factors of rhinitis and sinusitis and the physiological and anatomical characteristics of nasal cavity and sinus cavity, and on the basis of drawing lessons from the advantages and disadvantages of various drugs and treatment methods commonly used in clinic to treat this disease, and can achieve curative effect.
1. Prescription design
"Biyanling nasal drops" is designed according to the etiology and pathology of rhinitis and sinusitis: allergy, infection and mucosal inflammation. It has anti-inflammatory, antibacterial and antiallergic effects, such as sterilization, reducing inflammatory exudation, promoting secretion drainage, reducing sinus pressure and so on, and alleviating the clinical symptoms of patients from the etiology. It embodies the effect of treating both the symptoms and the root causes.
2. Method and dosage of medication
According to the physiological and anatomical characteristics of nasal cavity and accessory nasal cavity, referring to various clinical treatment methods, we improved and innovated, which made up for the shortcomings of small dosage of traditional nasal drops and the inability of liquid medicine to enter accessory nasal cavity. Take a supine position, take a large dose, and give it by nasal bath. Drop several milliliters of liquid medicine directly into the nasal cavity and sinus cavity at one time, so that the liquid medicine can directly contact with the mucosa of the diseased part, and give full play to its pharmacological effects.
3. It can be used in the whole process, fully and continuously.
The finished liquid medicine is colorless, odorless and non-irritating, so this product is used to treat rhinitis and sinusitis, which has little irritation and no pain to patients, and can dilute viscous secretions in sinus cavity to facilitate drainage and pus discharge.
The drug is targeted, and the drug only reaches the therapeutic concentration in the nasal cavity and accessory nasal cavity, and does not enter the blood circulation, which not only increases the treatment time of the drug and improves the curative effect, but also has no toxic and side effects on the patient's body. Therefore, the product can be used to treat rhinitis and sinusitis, and can be used continuously throughout the whole process, and is suitable for patients of all ages.
Eight, toxicology and pharmacology experiments
Pharmacological test results show that the drug has antibacterial, anti-inflammatory and antiallergic effects. The results of toxicology test showed that the lethal dose of the drug was 602 times of the normal clinical dose, and there were 1 10,000 patients in the first phase of clinical application without any toxic reaction.
Nine, clinical application
The pilot products have been used in the First People's Hospital of Jining City, Shandong Province and the Affiliated Hospital of Jining Medical College, Shandong Province for three years, treating more than 0/0000 cases of acute and chronic rhinitis, sinusitis and acute and chronic otitis media.
According to the feedback from clinical otolaryngologists and patients, the drug has the advantages of rapid action, definite curative effect, high cure rate, little irritation and no toxic and side effects. Can be clinically used for treating acute rhinitis, sinusitis and otitis media; It can effectively relieve symptoms such as memory loss caused by sinusitis in adolescents, especially for children with sinusitis. It can also prevent the occurrence of chronic rhinitis and sinusitis, showing its functions of treating both the symptoms and root causes and prevention. It is an ideal local therapeutic agent and substitute product for treating rhinitis, sinusitis and allergic rhinitis.
X. treatment of upper respiratory tract infection
"Biyanling Nasal Drops" is used to treat upper respiratory tract infection (cold), which has quick effect and good effect, and can quickly improve clinical symptoms. Relieve the disease and shorten the course of disease; Complete recovery can effectively prevent chronic rhinitis, sinusitis and respiratory complications. Treat both the symptoms and root causes, and prevent the effect! 1. Treatment of sinusitis:
The patient lies on his back with his head tilted back 80 degrees. Slowly drip the liquid medicine into the bilateral nasal cavity around the nasal margin. After dropping the medicine, lean back 10- 15 minutes, and then lie on your back for 30-60 minutes. This medicine works best when you sleep at night. Because of the long lying time, the liquid medicine stays in the sinus cavity for a long time and fully contacts with the inflamed mucosa, which improves the therapeutic effect. Adults take one tablet at a time, patients with serious illness take it once at noon and at night in the first week, and once at night in the second week. /kloc-children under 0/0 use half a pack at a time, once at noon and once at night.
2. Treatment of simple rhinitis and allergic rhinitis:
The patient was lying on his back with his head tilted back. Slowly drip the liquid medicine into bilateral nasal cavities around the nasal margin, and lie flat for 20-30 minutes after dripping. Adults use half a cigarette at a time, twice a day, once at noon and once at night. /kloc-children under 0/0 use 0.5-2ml each time, three times a day.
3. Treatment of cold: The patient lies on his back with his head tilted back, and the liquid medicine is slowly dripped into both nasal cavities around the nasal margin, and then he lies on his back for 20-30 minutes. Adults use half a cigarette at a time, 2-3 times a day. /kloc-0.5-2ml for children under 0, 2-3 times a day.