(2) Anti-cancer drug asparaginase, mainly produced by Liu Jingjing, has been included in China Pharmacopoeia (2000 edition) and won the second prize of Jiangsu Science and Technology Progress (ranking first). The project of "Enzymatic Production of Alanine" mainly completed in Liu Jingjing has also achieved industrial production in enterprises in the province and won the second prize of scientific and technological progress of the State General Administration of Medicine; Completed the "enzymatic production of D- p-hydroxyphenylglycine by genetically engineered bacteria" and passed the expert appraisal organized by the Science and Technology Department of Jiangsu Province (word [2002] No.321; Ranked first).
(3) In terms of technological innovation, the discipline idea of "Microgene Pharmacy" was put forward for the first time at home and abroad, and a series of related technical researches on major diseases were carried out along this research idea, and the "863" project of "Research on the Technical Platform of Microgene Pharmacy Preparation" was completed. The school established the related technical platform of "Microgene Pharmacy" as "2 1 1".
(4) The established research team with the research direction of micro-gene drugs has undertaken many national "863" plan projects, national natural science foundation projects and Jiangsu natural science foundation projects. The research direction mainly includes peptide drugs such as recombinant human insulin for treating diabetes, nucleic acid vaccines and protein vaccines for anti-tumor growth, protein drugs and vaccines for anti-atherosclerosis, parathyroid hormone analogues for anti-osteoporosis and other small peptide drugs, and the research funding is 1738.
(5) 25 national patents applied for and made public; He has published more than 50 papers1in core academic journals at home and abroad, including more than 40 SCI papers, and many papers have been published in JIMMOL (IF 6.293), JIBIOL CHEM (IF 5.808), INVEST Ophthalmol VISSCI (IF 5.2), ENOCR RELATE Cancer (IF 5.2) and vacuum (if 3./klcine).
(6) In the transformation of scientific research achievements, the anticancer drug asparaginase mainly completed by Liu Jingjing has been produced in Changzhou Hongqian Biochemical Pharmaceutical Factory, an enterprise in Jiangsu Province, and the products have been used in major hospitals in China and exported to India and other countries, creating tens of millions of economic benefits and winning the second prize of scientific and technological progress in Jiangsu Province; The project of "Enzymatic Production of Alanine" mainly completed in Liu Jingjing has also achieved industrial production in enterprises in the province, and won the second prize of scientific and technological progress of the former State General Administration of Medicine; Completed the "enzymatic production of D- p-hydroxyphenylglycine by genetically engineered bacteria" and passed the expert appraisal organized by Jiangsu Science and Technology Department (ranked first).