Name: A new human gene P53bp3 interacting with the anticancer gene p53.
Gong Kai (Announcement)No.: CN 1 178243 Publication (Announcement) Date: 1998.04.08.
Main classification number: C 12N 15/ 12 Original application number:
Classification number: C 12N 15/ 12.
Release Date: Priority:
Applicant: Shanghai Institute of Biochemistry, Chinese Academy of Sciences.
Address: No.320 Yueyang Road, Shanghai, 20003 1
Inventor (Designer): Ao Shizhou; Zhou Rui's international application:
International publications: Entry date:
Patent Agency: Shanghai Huadong Patent Office Agent: Fei Kaikui.
abstract
The present invention relates to a human protein gene P53BP3 interacting with an anticancer gene coding product P53, the cDNA of which consists of 5055 nucleotides, and the coding sequence codes for protein with 8 15 amino acids. It is widely expressed in human normal tissues and tumor cell lines. The P53BP3 gene is located in the fragment of chromosome11.2—12.1