The main tasks of HGP are human DNA sequencing, gene mapping, physical mapping, sequence mapping and gene mapping, as well as sequencing technology, human genome sequence variation, functional genome technology, comparative genomics, social, legal, ethical research, bioinformatics and computational biology, education and training.
Meaning:
1 and HGP's contribution to human disease gene research
Genes related to human diseases are important information for the structural and functional integrity of human genome. For a single base
2. Contribution of 2.HGP to medicine
Gene diagnosis, gene therapy and therapy based on genome knowledge, disease prevention based on genome information, identification of susceptible genes, lifestyle of risk population and intervention of environmental factors.
Due to illness, a brand-new idea of "positional cloning" and "positional candidate cloning" was adopted, which led to the discovery of a large number of single-gene hereditary diseases such as Huntington's disease, hereditary colon cancer and breast cancer, and laid the foundation for gene diagnosis and gene therapy of these diseases.
Extended data:
Human Genome Project-Achievements
1860 rpm 1870:? Austrian scholar Mendel put forward the concept of genetic factor according to pea hybridization experiment, and summarized Mendel's genetic law.
1909: Danish botanist and geneticist Johnson put forward the word "gene" for the first time, expressing Mendel's concept of genetic factors.
1944: Three American scientists isolated bacterial DNA (deoxyribonucleic acid) and found that DNA is a molecule that carries the genetic material of life.
1953: American Watson and British Crick put forward the double helix model of DNA molecules through experiments.
1969: Scientists successfully isolated the first gene.
References:
Baidu Encyclopedia-Human Genome Project