The results of antigen detection by COVID-19 latex method and colloidal gold method are inconsistent.

The reasons for the inconsistency between COVID-19 latex method and colloidal gold method in detecting antigens are as follows:

1, the principle is different: novel coronavirus detection latex method is non-selective physical electrostatic adsorption, antibody is difficult to bind to latex surface, and the manufacturing process is time-consuming. Colloidal gold method has negative hydrophobic colloidal solution and electrostatic effect.

2. Different carriers: novel coronavirus test latex method is to observe the test results through the combination of ordinary polystyrene latex and antibody, while colloidal gold method is a particle polymerized by chloroauric acid under the action of various reducing agents.