Some distinctive research achievements of Xue-Gang Li.

① Comprehensive development and utilization of Coptis chinensis: presided over "Research on standardized planting base of Coptis chinensis in Shizhu and its SOP optimization and upgrading" (supported by the Ministry of Science and Technology), "Comprehensive development and utilization of Coptis chinensis" (a major project of Chongqing Science and Technology Commission), "Planning of Coptis chinensis industrial chain project" (a project of Chongqing Development and Reform Commission), "Development and utilization of Coptis chinensis by-products" (a special project of Chongqing Municipal People's Committee) and "Extraction technology and pilot test of Coptis chinensis total alkaloids" (a key project of Shizhu County). The key technologies such as deep processing of Coptis chinensis, development and utilization of Coptis chinensis by-products, extraction and separation of effective components of Coptis chinensis, and structural modification were systematically and deeply studied: 8 technological invention patents 18 were declared and 2 were authorized 12; Nearly 75 related academic papers were published, and 22 were included in Sci; "Comprehensive Development and Utilization of Coptis chinensis" won the second prize of Chongqing Technological Invention (2013); The new drug "Huanglianxu (William) Chinese Veterinary Medicine" (Class II) obtained the clinical approval (Nong Yu Medical Letter [2065438+02] No.7); It is at the national leading level in the comprehensive development and utilization of Coptis chinensis and deep processing research and development.

② Research and development of new drugs for lowering blood sugar and blood fat: According to the requirements of Measures for the Administration of Drug Registration, Supplementary Provisions on the Administration of Chinese Medicine Registration and Guiding Principles of Chinese Medicine Research Technology, and based on the basic principle of "safety, effectiveness and controllable quality" (Chongqing), Pingshushu Capsule, a hypoglycemic hospital preparation with Rhizoma Coptidis (total alkaloids) as the main raw material, was approved.

③ "production of medicinal amino acids". The produced histidine hydrochloride has reached the quality standard of Ajisen in Japan, achieving an annual output of more than 2 tons of histidine hydrochloride, becoming the first domestic enterprise to produce histidine hydrochloride industrially, filling the domestic gap. While producing histidine hydrochloride, arginine hydrochloride and arginine base, lysine series and tyrosine series are also co-produced. The project has been industrialized. And obtained the technical invention patent (patent number: 0 1 132740.5).

④ Comprehensive development and utilization of capsicum (extraction of capsanthin and capsaicin and utilization of capsicum residue). Help enterprises to complete the task of expanding production scale and participate in the whole set of industrial production and design. The solvent consumption is reduced by three quarters, the yield is increased by 65438 00%, and the product quality is significantly improved (the solvent residue is reduced to below 65438±300 ppm); More than 90% capsaicin products and high-purity capsanthin products with color value greater than 300 have been developed.