Influenza is a very common disease, and everyone is very aware of it, especially in autumn every year, which is the period of influenza outbreaks. Everyone must take precautions. Although there is a vaccine against influenza virus, more people are willing to take medicine instead of injections. So what are the anti-flu virus drugs? What kind of medicine is Tamiflu? Let’s take a look.
1. What is Tamiflu?
Tamiflu currently on the market is an anti-influenza drug exclusively produced by Roche Pharmaceuticals. Its generic name is Oseltamivirphosphate. Oseltamivir was launched in Switzerland in 1999 and in my country in October 2001. Tamiflu is a very effective drug for treating influenza and can greatly reduce the occurrence of complications (mainly tracheitis and bronchitis, pneumonia, pharyngitis, etc.) and the use of antibiotics. Therefore, it is currently one of the most commonly used drugs for treating influenza. , is also recognized as one of the most effective drugs against avian influenza and influenza A H1N1.
2. Side effects
Generally, the side effects of Tamiflu are abdominal pain, nausea, vomiting or diarrhea, which are relatively common phenomena. If these symptoms are severe or there is no sign of improvement, Please go to the hospital in time for check-up to avoid delaying treatment of the disease. The medicine is in the form of capsules, which are gray white and light yellow two-color capsules. It can be taken orally. The dosage is calculated based on body weight. The dosage of medicine is different for people with different weights. It is recommended that we read the instructions carefully or ask questions. The doctor will handle it and take it according to the doctor's instructions. If you have any discomfort, please check it in time to avoid delaying treatment. Friends who are allergic to the ingredients of Tamiflu should avoid taking the medicine. For people with allergies themselves, please consult a doctor whether they can take it.
Tamiflu still has some side effects, so we cannot take the drug just because it has good effects. Only symptomatic medication can effectively treat the disease. Children and elderly patients should follow the doctor’s advice. Do not take it. Indiscriminate use of drugs. Otherwise, the damage to the body will be great.
3. Functional Indications
Roche’s Tamiflu was approved for marketing by the US FDA in 1999 and was launched in China in July 2004. From the perspective of pharmacoeconomics, although the cost of using Roche's Tamiflu is not low, taking it twice a day, 75 mg each time, the retail price of the drug is equivalent to 60 yuan per day, and a five-day course of treatment is equivalent to about 300 yuan. However, because Roche Tamiflu is a very effective drug for treating influenza and can greatly reduce the occurrence of complications (mainly trachea and bronchitis, pneumonia, pharyngitis, etc.) and the use of antibiotics, it is currently the most commonly used drug for treating influenza. One of the most effective drugs against avian influenza and swine flu (A/H1N1 virus).
Oseltamivir phosphate is the prodrug of the active metabolite of Roche Tamiflu, which is a potent and selective inhibitor of influenza virus neuraminidase. Viral neuraminidase activity is critical for the release of newly formed viral particles from infected cells and further spread of infectious virus in the human body. The active metabolite of the drug inhibits neuraminidase of influenza A and B viruses. In vitro inhibitory effects occur at very low nanomolecular concentrations. Active metabolites have been observed to inhibit influenza virus growth in vitro and inhibit influenza virus replication and pathogenicity in vivo.
In addition to Roche Tamiflu, oseltamivir phosphate is recommended for influenza prevention after close contact with influenza patients. The oral dose is 75 mg once daily for at least 10 days. Medication should also be started within 2 days of close contact. There is data showing that the drug is safe and effective when used continuously for 6 weeks, and it has a preventive effect during the period of taking the drug.
4. Symptoms of H1N1 flu
Symptoms of H1N1 flu are very common and there is no need to cause panic, but you should not avoid medical treatment. Once you find that you have cold symptoms, you should go to the hospital for medical treatment immediately. The hospital has dedicated passages for fever, which is very convenient. The virus is a subtype of influenza A and contains both human and poultry and pig gene segments. Compared with ordinary seasonal influenza, it spreads more strongly.
When you find that you have symptoms of influenza A, you should take active treatment. It is recommended to wear a mask when seeking medical treatment. Generally, patients will have dry throat, itching, pain, runny nose, cough, and some patients will have fever. .
The initial symptoms of influenza A are similar to those of ordinary influenza. General symptoms include the absence of fever in some patients, so patients without fever cannot be completely ruled out.
If the symptoms of influenza A are not actively treated, it can easily affect personal health. In addition, there are systemic symptoms, such as fatigue, muscle aches, and digestive tract symptoms such as diarrhea and stomachache. Intestinal dysfunction, etc. Some individuals show abnormalities in other organs, but most symptoms are mild.