chlorantraniliprole is the second amide insecticide developed by DuPont Company in 2 to circumvent the patent of fipronil diamide and modify it on the basis of fipronil diamide. It was first listed in the Philippines in 28 under the trade name of "Kangkuan". Mainly by activating the carnitine (muscle) receptor in pests. It causes excessive release of intracellular calcium ions, which eventually leads to paralysis and death of pests. Chlorfenapyramide mainly has contact toxicity and stomach toxicity, with broad insecticidal spectrum, high activity, systemic conductivity, long duration, and is not easy to produce drug resistance, especially for the larvae of Lepidoptera pests. Generally, pests stop their activities after feeding for 3-5 hours and reach the peak of insect death in 5-7 days. According to the current test results, the activity of chlorantraniliprole against target pests is 1~1 times higher than that of other products, and it has a good control effect on Lepidoptera, such as Noctuidae, Mothidae, Fruit-moth-eating Mothidae, Myxomycetes, Lepidoptera, Lepidoptera, Lepidoptera and Lepidoptera. A variety of non-Lepidoptera pests such as Diptera, Diptera and Diptera. It is safe for crops and has low toxicity to people, animals, bees, fish, shrimp and other environmental insects. Because the patent period has passed, the price has also dropped greatly. It is the most widely used pesticide at present. However, due to the use of a single preparation for many years in some areas, drug resistance has emerged and the control effect has gradually decreased.
tetrachloropyramide, also known as 98, is the fourth diamide compound with high insecticidal activity-tetrachloropyramide, which was discovered by Shenyang Research Institute of Chemical Industry under Sinochem Group in 28, with chlorantraniliprole as the lead compound, through structural modification of benzene ring substituents and pyrazole substituents in its structure. It was successfully listed in 214 with the trade name "98". It opens the calcium ion channel by binding with the carnitine receptor in the insect body, so that the calcium ion stored in the cell is continuously released into the sarcoplasm, and the calcium ion is combined with the matrix protein in the sarcoplasm, causing the muscle to continuously contract. The physical symptoms of insects are convulsions, refusal to eat and final death.