Introduction to children's heat-clearing and phlegm-resolving suppositories

Contents 1 Pinyin 2 Standards issued by the Ministry of Traditional Chinese Medicine 2.1 Pinyin name 2.2 Standard number 2.3 Prescription 2.4 Preparation method 2.5 Properties 2.6 Identification 2.7 Inspection 2.8 Function and indication 2.9 Usage and dosage 2.10 Specifications 2.11 Storage Appendix: 1 In ancient books Children's Qingre Huatan Shuan 1 Pinyin

xiǎo ér qīng rè huà tán shuān 2 Standard 2.1 issued by the Ministry of Traditional Chinese Medicine Pinyin name

Xiao'er Qingre Huatan Shuan 2.2 Standard number

WS3B375698 2.3 Prescription

Bezoar 8g, buffalo horn 120g, honeysuckle 160g, forsythia 120g, rhubarb 20g, baicalin 12g, gypsum 40g, green stone (forged) 40g, fritillary 60g. 60g light bamboo leaves, 40g licorice 2.4 Preparation method

For the above eleven flavors, except bezoar, grind it into fine powder, take buffalo horn file coarse powder, add water and boil twice, 4 hours each time, filter, filtrate Concentrate and dry; add licorice, raw gypsum, and calcined limestone coarse powder (decoction) in water and boil twice for 2 hours each time, filter, and the filtrate is concentrated and dried; except for baicalin, the remaining five flavors such as honeysuckle and vine are boiled in water for two times. Filter, 2 hours each time, and concentrate the filtrate to a clear paste with a relative density of 1.14 to 1.18 (measured at 80°C). Add ethanol to make the alcohol content 60, stir, and let stand for 24 hours. Take the supernatant. For later use, the residue is washed with 10% ethanol, the washing liquid and the supernatant are combined, the ethanol is recovered under reduced pressure, concentrated to a thick paste with a relative density of 1.34 to 1.39 (measured at 55 to 60°C), and dried; the above dry paste is crushed with baicalin into Fine powder; take semi-synthetic fatty acid ester, add the above-mentioned fine powder (powder: matrix = 1:2) at 45°C, cast it into a mold, and cool it.

2.5 Properties

This product is a brown torpedo-type suppository. 2.6 Identification

Take 2 tablets of this product, add 50ml of water, dissolve on a water bath, let cool, filter, concentrate the filtrate to about 25ml, add 20ml of ether, shake and extract, discard the ether liquid and water liquid. Evaporate to dryness, add 20 ml of absolute ethanol, reflux and extract for 30 minutes, let cool, filter, and concentrate the filtrate to 5 ml as the test solution; take other cholic acid and hyodeoxycholic acid reference substances, and add absolute ethanol to make them. Each 1ml contains 2mg of solution as reference solution. According to the thin layer chromatography (Appendix VI B) test, draw 2 μl of each of the above three solutions, place them on the same silica gel G thin layer plate, use chloroform, ether, glacial acetic acid (4:5:1) as the developing agent, develop and take out , dried, sprayed with an ethanol solution of 10% phosphomolybdic acid, and baked at 105°C until the spots were clearly colored. In the chromatogram of the test product, the same blue spots appear at the positions corresponding to the chromatogram of the reference substance. 2.7 Inspection

It should comply with the relevant regulations under suppositories (Appendix I W). 2.8 Functions and Indications

Clear away heat and detoxify, resolve phlegm and relieve cough. It is used for coughs and wheezing caused by excessive phlegm-heat and decreased lung qi, yellow and sticky phlegm, dry and red stools, high fever and convulsions. 2.9 Usage and dosage

Rectal administration, 1 capsule at a time, 2 to 3 times a day or as directed by your doctor. 2.10 Specifications

Each grain weighs 0. 9g 2.11 Storage

Keep in a cool place.

Drafted by the Heilongjiang Provincial Institute for Drug Control. The antipyretic and phlegm-resolving suppositories for children in the ancient book "Dantai Jade Case": [Volume 6] Cold Gate

Clearing away the heat will make the disease better.

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The disease will be cured after the power is dispersed. A child's face is pale, he suffers from thirst, and his saliva produces fever. He takes medicine to clear away heat and resolve phlegm. He has diarrhea and frequent urination. This is because the spleen and stomach are weak and injured again. In the morning... "Chen's Secrets of Preschool Medicine": convulsions

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