Scientific research achievements of Jiangsu Medical Research Institute

Jiangsu Institute of Medicine has strong research and development ability of new drugs, and has made good achievements in the research and development of new drugs. * * * Obtained 139 national new drug certificate. The conversion rate of new drug achievements is over 98%. Antimony 273 is a sustained-release preparation for treating schistosomiasis, which was successfully researched in 1970s. It is the first sustained-release preparation in China Pharmacopoeia. Amphotericin B liposome for injection and paclitaxel liposome for injection have become the first liposome dosage forms listed in China.

In the past 20 years, the Institute has undertaken a total of National Natural Science Foundation projects 12, 5 national key projects, 8 national new drug funds, 2 world bank loans, 53 provincial and ministerial key projects, 42 international cooperation projects 10, and more than 700 domestic horizontal cooperation projects. More than 50 research achievements won awards (including international award 1, 5 national awards and 26 provincial awards), and 34 invention patents were obtained. He has published more than 800 papers in various academic journals at home and abroad, and has written and participated in the compilation of more than 20 monographs and translations. In international exchanges, the Institute has successively conducted academic exchanges with the United States, Britain, France, Japan, Germany, Sweden, Belgium, Australia, Southeast Asia and other countries, and received nearly 50 batches of experts 100, and cooperated with the World Health Organization (WHO), the International Organization for the Development of Chemical Science (IOCD), the Institute of Ophthalmology and Pharmacology of Texas A&M University, and the United States.

On the basis of long-term pharmaceutical basic science and applied research, the technical platform and technical advantages of new drug creation have been constructed in some research fields. Our hospital has carried out many years' research on chemical composition and activity screening of natural products, and developed natural drugs such as armillarisin A, total saponins of Astragalus membranaceus and total coumarin of Fructus Cnidii. The research of sustained (controlled) release preparation technology and liposome technology has reached or basically reached the international similar research level.

With the completion and operation of infrastructure, it will be beneficial to give full play to the scientific research strength of new drug innovation and development of Jiangsu Institute of Pharmacology, and improve the innovation level and industrialization level of "three drugs" in Jiangsu Province. In order to meet the needs of China's entry into WTO, the creation project of "Three Drugs" in Jiangsu Province and the transformation of research institutes, Jiangsu Institute of Medicine will give full play to its own advantages, strengthen external contacts and cooperation, promote the effective combination of science and technology and economy, and strive to develop into a new research institute that integrates production, learning, research, science, industry and trade, relying on the research and development of new drugs and relying on the leading industrial base of science and technology.