Recently, a research team composed of personnel from the University of Tokyo and other institutions announced the results of animal experiments on Omicron BA.5 subtype strains. The results showed that strain BA.5 was more pathogenic and more likely to cause inflammation than the early Omicron mutant.
The research team made viruses with the characteristics of BA.2 and BA.5 in Omicron, infected cultured cells with the virus and observed their growth. The research team said that this is only an experimental result on animals, and the actual symptoms reflected in humans need further observation.
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BA.5, a subfamily of Omicron, has become the main epidemic strain in South Africa, Portugal and other countries, and there are also local epidemic reports caused by imported cases of this strain in Beijing, Tianjin and Shaanxi.
Unique mutations of spike proteins 452 and 486. Omicron BA.5 subfamily strain enhanced the binding ability between virus and host cells, showed certain immune escape characteristics to the specific antibodies induced by existing vaccines or previous infections, reduced the protective power of vaccination, and made subfamily strains more infectious and the incubation period after infection shorter.