With the progress of the disease, after entering the end-stage renal disease, the outflow of hyperosteogeny is further aggravated, resulting in ductile fractures, which seriously affects the quality of life of patients and increases their mortality. Analysis shows that the incidence of osteoporosis in CKD can reach 47.65438 0%, and the incidence increases slowly with the decrease of glomerular filtration rate.
Generally, within 30 to 35 years old, the maximum bone mass can be obtained in a lifetime, which is called the maximum bone mass, and then the bone mass is gradually lost with the increase of age. The imminent problem of osteoporosis is that the professional ability of bone load is reduced, and fractures are prone to occur, which may seriously affect the work and life of osteoporosis patients.
The inducement of osteoporosis can be divided into two categories. One is primary, including senile osteoporosis, postmenopausal osteoporosis and refractory osteoporosis. The other is primary, generally caused by pregnancy, lack of nutrition, lack of sunshine, lack of physical exercise and so on. And there are some reasons that are often overlooked by others, such as medical diseases, malignant tumors and kidney diseases.
Generally speaking, patients with kidney disease should find and diagnose osteoporosis as soon as possible and make risk assessment. Serum protein calcium, phosphorus, alkaline phosphatase (ALP), parathyroid hormone (PTH) and 25(OH)D(25- hydroxyvitamin D) should be checked on time, and bone mineral density should be checked if necessary to assess the risk of fracture. At the same time, active intervention and treatment can reduce the risk of falls and fractures, and then have a better quality of life and recovery than the flood level.