New progress has been made in domestic therapeutic drugs for COVID-19.

On 202 1 12, the State Administration of Pharmaceutical Products approved the application for registration of neutralizing antibody combined therapy drugs in COVID-19, namely Ambavirmonoclonal antibody injection (BRII- 196) and romisvimab injection (BRII- 198). This is the first COVID-19 neutralizing antibody combination therapy drug approved by China with independent intellectual property rights.

In July, 2022, the State Administration of Pharmaceutical Products conditionally approved the application for increasing the indications of afudin tablets for COVID-19. This is an oral small molecule COVID-19 drug independently developed by China.

Previously, in the anti-epidemic struggle in Wuhan, Hubei Province, relevant academicians and experts led a team of researchers to screen out Chinese medicines in view of the lack of specific drugs and treatment needs in the early stage? Three drugs and three parties? COVID-19 and other drugs provide a strong guarantee for the treatment.

Liu Dengfeng, inspector of the Science and Education Department of the National Health and Wellness Commission, said that after the COVID-19 outbreak, the joint prevention and control mechanism in the State Council organized drug research and development at the first time, and did a lot of work in pre-clinical drug research, antibody screening, clinical trial resource planning and rapid review and approval. Based on the platform and team of drug screening, vaccine research and development, clinical evaluation and other major projects of national new drug creation, we quickly promoted the successful listing of neutralizing antibodies, chemical drugs and traditional Chinese medicines.

It is understood that there are still a variety of COVID-19 drugs in different stages of research and development in China, and some drugs have been carried out phase III clinical trials at home and abroad.

According to the person in charge of the scientific research team of the State Council Joint Prevention and Control Mechanism, at present, the research and development of therapeutic drugs in COVID-19 mainly focuses on three technical routes: blocking virus from entering cells, inhibiting virus replication and regulating human immune system, which are deployed in China.

Since its establishment on February 6th, 2020, the drug research and development special class of the State Council Joint Prevention and Control Mechanism Research Group, which is composed of the Ministry of Science and Technology, the National Health and Wellness Commission, the Ministry of Industry and Information Technology, the National Development and Reform Commission, the State Administration of Pharmaceutical Products, and state administration of traditional chinese medicine, has organized a national team of outstanding experts to fully promote the research and development of effective drugs and treatment technologies.