What is the difference between paclitaxel liposome and paclitaxel?

The differences between paclitaxel liposome and paclitaxel are: different indications, different preparation methods and different physical and chemical properties.

First, the applicable diseases are different.

1. paclitaxel liposome: used for first-line chemotherapy of ovarian cancer and the treatment of metastatic ovarian cancer in the future.

2. Paclitaxel: It has been widely used in the treatment of breast cancer, ovarian cancer and some head and neck cancers and lung cancer.

Second, the production methods are different.

1. paclitaxel liposome: the main component of this product is paclitaxel, and the auxiliary materials are lecithin, cholesterol, threonine and glucose.

2. Paclitaxel: a natural secondary metabolite isolated and purified from the bark of gymnosperm Taxus chinensis, which is pure.

Third, the physical and chemical properties are different

1. paclitaxel liposome: this product is a white or yellowish block with a slight lecithin smell.

2. Paclitaxel: Paclitaxel is a white crystalline powder, odorless and tasteless, insoluble in water, and easily soluble in organic solvents such as methanol, acetonitrile, chloroform and acetone.

Baidu encyclopedia-paclitaxel liposome for injection

Baidu encyclopedia-paclitaxel