The present invention relates to a method for continuously producing n-butane chloride using n-butanol and hydrochloric acid as raw materials, and belongs to an organic synthesis process. This n-butane chloride is particularly suitable as a synthetic raw material for n-butyllithium used as an anionic polymerization catalyst.
In the existing technology, n-butanol chloride and hydrochloric acid or hydrogen chloride are used as raw materials to synthesize n-butane chloride, which is mostly produced with an external catalyst, especially ZnCL2 as the catalyst. This method has many side reactions. A large amount of butene, dibutyl ether and polymer resin are generated during the reaction. The product contains a large amount of chloro-sec-butane. The recovery of ZnCL2 after the reaction is also very troublesome and is not suitable for continuous production.
CZech148,798 and CZech148,797 patents produce chloron-butane through the reflux reaction of 1 mole of n-butanol and 3 mole excess of hydrochloric acid or a mixture of hydrogen chloride and hydrogen bromide. The amount of hydrochloric acid or its mixture with hydrogen bromide used in this method is too large, resulting in high consumption, and no treatment measures are proposed for the alcohol and acid in the discharged water. If a mixture of hydrochloric acid and hydrogen bromide is used to react with n-butanol, sec-butane bromide will be produced in the product, which will reduce the yield and purity of n-butane chloride.