Hematopoietic stem cells are mainly divided into three stages:
1, the initial stage of hematopoietic stem cells, the stem cells of hematopoietic cells in this stage, they can not only keep their own number stable through self-renewal, but also differentiate into directional progenitor cells of various lines;
2. The stage of directional progenitor cells, in which the direction of further differentiation of hematopoietic cells is defined, which can be divided into multi-line directional progenitor cells, red blood cells, granulocyte-monocyte progenitor cells, megakaryocyte progenitor cells and TB lymphocyte progenitor cells;
3. In the stage of morphologically recognizable precursor cells, hematopoietic cells have developed into immature cells of various lines with morphologically recognizable shapes, which mature into various terminal blood cells with special functions and then are regularly released into the blood circulation.
Extended data:
Other stem cells in the human body:
1, embryonic stem cells are the most attractive in the research and application of various stem cells. Embryonic stem cells (ESCs) refer to cells screened by inhibiting cell clusters or primordial germ cells in embryos in vitro. In addition, embryonic stem cells can also be obtained by somatic cell nuclear transfer technology.
Embryonic stem cells have developmental totipotency and can be induced to differentiate into various cells in vivo theoretically. Embryonic stem cells can be expanded, screened, frozen and revived in vitro without losing their original characteristics.
2. Adult stem cells Adult stem cells refer to undifferentiated cells that exist in differentiated tissues. They can renew themselves and specialize to form cells that constitute this type of tissue. Adult stem cells exist in various tissues and organs of the body.
The adult stem cells found mainly include hematopoietic stem cells, bone marrow mesenchymal stem cells, neural stem cells, liver stem cells, muscle satellite cells, skin epidermal stem cells, intestinal epithelial stem cells, retinal stem cells, pancreatic stem cells and so on.
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