Commonly used drug pairs to treat gout attacks

膆薢 and Alisma

膆薢 has a neutral nature and a bitter taste. It belongs to the kidney and stomach meridians. It has the effects of diuresis and turbidity, wind and numbness, and is used to treat creamy stranguria, Rheumatic arthralgia, joint discomfort, waist and knee pain, etc. Alisma is cold in nature, sweet and light in taste, and belongs to the kidney and bladder meridian. It has the effects of diluting dampness, releasing heat, reducing turbidity and reducing lipids. It is used to treat difficulty in urination, swelling and fullness, diarrhea and oliguria, and hot stranguria and astringent pain. Hyperlipidemia, etc. When gout syndrome is characterized by damp-heat paralysis, the two medicines are often used in conjunction with each other, and the effect is remarkable. Pharmacological studies have found that the aqueous extract and total saponins of Pagoda japonica have significant effects on lowering uric acid, anti-inflammatory, analgesic, and anti-osteoporosis.

Atractylodes and Phellodendron

Atractylodes is warm in nature, pungent and bitter in taste. It returns to the spleen, stomach and liver meridians. It can remove dampness and strengthen the spleen, dispel wind and cold, improve eyesight, and is mainly used to treat dampness. Middle burner, abdominal distention, diarrhea, edema, rheumatic arthralgia, etc. Cortex Phellodendri is cold in nature and bitter in taste. It returns to the kidney and bladder meridian. It has the effects of clearing away heat and dampness, purging fire and relieving troubles. It is used for damp-heat diarrhea, jaundice, red urine, vaginal itching, hot stranguria and astringent pain, sores and swelling. , eczema eczema. The combination of Atractylodes and Cortex Phellodendron, also known as Ermiao Powder, has the effect of clearing away heat and drying dampness, and can be used as a basic prescription for damp-heat syndrome. During the acute attack of gout, the symptoms of internal dampness and heat are often present. The disease is located in the middle and lower burners, and is often accompanied by pathological products such as moisture, poison, and heat. The clinical manifestations are dry mouth, bitter chest, sticky stool, yellow and greasy tongue coating, etc. . Modern pharmacology suggests that Phellodendron cork and Atractylodes extracts can significantly reduce serum uric acid levels.

Polygonum cuspidatum and cinnamon twig

Polygonum cuspidatum is slightly cold in nature and slightly bitter in taste. It belongs to the liver, gallbladder, and lung meridian. It has the effects of diuresis and reducing jaundice, clearing away heat and detoxification, dispersing blood stasis and relieving pain. Mainly used to treat damp-heat jaundice, stranguria, leukorrhagia, rheumatic paralysis, carbuncle, sores, etc.; Guizhi is warm in nature, pungent and sweet in taste, and is directed to the heart, lung, and bladder meridians. It has the effects of sweating and relieving muscles, warming meridians and unblocking meridians, and is mainly used to treat wind-cold symptoms. Symptoms include cold-damp arthralgia, cold limbs, etc. The treatment of gout should focus on eliminating evil spirits, focusing on clearing away heat and detoxifying, diluting dampness and purging turbidity. Polygonum cuspidatum removes dampness and removes heat, while cinnamon twig warms the meridians and unblocks the meridians. The two medicines are used together. One warms and the other cold complements each other. It is cold but does not coagulate blood, and warm but does not help heat. It is suitable for people with little heat symptoms. Therefore, traditional Chinese medicine with anti-inflammatory and analgesic effects, represented by Polygonum cuspidatum, is often used during acute attacks of gout, which can effectively relieve symptoms. Studies have shown that Polygonum cuspidatum and Guizhi have a significant inhibitory effect on acute inflammation of gouty arthritis, which can effectively relieve joint swelling and pain, reduce inflammatory cell infiltration in the joint synovium and vascular congestion.

Smilax cocos and coix seed

Smilax poria cocos has a neutral nature, sweet and light taste, and returns to the liver and stomach meridian. It has the effects of detoxification, dehumidification, and joint relief. It is mainly used to treat limb spasm. , muscle and bone pain, damp-heat stranguria, leucorrhea, carbuncle, paralysis, etc., "Compendium of Materia Medica" states that "Smilax can strengthen the spleen and stomach and remove rheumatism. If the spleen and stomach are strong, the body will be nourished and defended, and the rheumatism removed will benefit the muscles and bones." Coix seed is cool in nature, sweet and light in taste, and returns to the spleen, stomach, and lung meridians. It has the functions of diluting water to penetrate dampness, strengthening the spleen and stopping diarrhea, removing paralysis, draining pus, detoxifying and dissipating stagnation. It is mainly used to treat edema, athlete's foot, dysuria, and spleen deficiency. Diarrhea, dampness-induced cramps, lung abscess, intestinal abscess, etc. Smilax cocos and coix seed are used together. They are sweet and light in dampness, but have weak heat-clearing power. They are specially used to clear away turbidity, detoxify, and relieve joints. They are the basic medicinal pair for the treatment of gout in the remission period. Modern pharmacological research shows that Smilax cocos has analgesic, diuretic, and antibacterial effects, while Coix Seed also has anti-inflammatory and analgesic effects.

Plantago and corn silk

Plantago is cold in nature and sweet in taste. It enters the bladder, spleen and kidney meridians and has the effects of diuresis, clearing away heat, improving eyesight and eliminating phlegm. , mainly used to treat swelling and fullness, hot stranguria, astringent pain, etc. Modern pharmacological research shows that psyllium can not only promote the excretion of uric acid, but also inhibit the synthesis of uric acid. It can quickly reduce the concentration of blood uric acid, reduce the excretion of uric acid in the urine, and prevent gout. It prevents the formation of stones and can effectively relieve joint swelling and pain. Corn silk is neutral in nature, sweet and light in taste, and belongs to the bladder, liver, and gallbladder meridians. It can relieve heat and relieve stranguria, diuresis and swelling, cleanse the liver and gallbladder, and treat edema, stranguria, hypertension, diabetes, etc. The combination of the two medicines can not only clear away heat and dampness, but also diuresis and swelling, promote uric acid excretion, and relieve joint pain and swelling.

Salvia miltiorrhiza and turmeric

Salvia miltiorrhiza is bitter in taste and cold in nature. It returns to the heart and liver meridian. It can activate blood and cool blood, remove blood stasis and eliminate carbuncle, stimulate menstruation and relieve pain. It is used for chest pain, heartache and epigastrium. Hypochondriac pain, heat numbness pain, etc. Turmeric is warm in nature, pungent and bitter in taste. It can promote qi and blood stasis, unblock collaterals and relieve pain. It is mainly used to treat chest and abdominal distension and pain, shoulder and arm paralysis, irregular menstruation, and bruises. Pharmacological studies have found that Salvia miltiorrhiza extract can promote uric acid excretion and reduce serum uric acid.

Turmeric extract can inhibit the activity of xanthine oxidase in liver tissue, thereby reducing the production of uric acid and promoting the excretion of urinary uric acid, thereby achieving the purpose of reducing serum uric acid. When combined with turmeric and dandelion, it can not only cool the blood and activate blood circulation, but also relieve qi and dissipate stagnation. It has a significant effect on relieving joint swelling and subcutaneous nodules in patients with chronic gout.