The most acute cases began diarrhea 1 day after birth, and the hindquarters were covered with blood samples and thin feces. The sick pig gradually weakened, refused to walk, and soon entered a state of near death. It is easy to be trampled by sows, and the rectal temperature drops to 35℃. Before death, the abdominal skin turns black, and some sick pigs may die without diarrhea. The course of acute cases usually lasts for 2 days and usually dies on the third day. Generally, there is no hemorrhagic diarrhea in subacute cases, and yellow feces are discharged, and then become liquid, containing gray necrotic tissue fragments, similar to rice porridge, emaciation and dehydration, and generally die in 5 ~ 7 days. Chronic cases are characterized by intermittent or persistent non-hemorrhagic diarrhea, which is easily confused with yellow and white diarrhea in piglets, and the effect of treating yellow and white diarrhea with drugs is not good.
Pregnant sows injected with combined vaccine of Clostridium welchii type A and C can prevent the occurrence of Clostridium enteritis.