How to treat and prevent porcine circovirus?

Porcine circovirus disease is a new infectious disease of pigs caused by porcine circovirus type ⅱ, which infects pigs of 8 ~ 13 weeks old. Clinical symptoms are diverse, such as multiple system weakness syndrome in weaned piglets, dermatitis nephrotic syndrome, porcine respiratory syndrome, enteritis, reproductive disorder, congenital paroxysmal fibrillation in newborn piglets and so on. Among them, weaned piglets with multiple system weakness syndrome, dermatitis nephrotic syndrome and reproductive disorder are common in clinic, which are harmful to pig industry. The disease can infect pigs of different ages through oral and respiratory routes, and the articles or secretions (blood, urine, feces or mucus) of sick pigs may contain infectious pathogens. After pregnant sows are infected with the virus, they can also infect piglets through vertical transmission of placenta, causing reproductive disorders.

Weaned piglets with multiple system weakness syndrome often show poor growth and development, gradual emaciation, weight loss, pale skin and visible mucosa or jaundice, anemia, fatigue, dyspnea, cough, asthma, partial diarrhea and obvious swelling of inguinal lymph nodes. With the development of the disease, the sick pig had purple eyes, blue ears and cyanosis, and finally died of suffocation.

Pigs with dermatitis nephrotic syndrome are characterized by irregular reddish-purple spots and papules on the skin, which first appear on the back, limbs and abdomen of pigs, and then spread to the chest, back and ears. Eyes can see round or irregular red to purple spots and papules with different shades, which combine in perineum and limbs to form irregular patches. With the extension of the course of disease, the lesion area ruptured and scabbed in black. Mild people have low body temperature and slow growth, while severe people have elevated body temperature, anorexia and limping (only one hind leg tarsal joint is swollen).

Preventive and control measures

(1) Inoculated with porcine circovirus vaccine, it is recommended to use genetically engineered vaccine inactivated vaccine.

(2) Improve the traditional feeding management of pig farms. If conditions permit, synchronous production by stages and feeding at two or three points shall be adopted as far as possible.

(3) Strengthen feeding management, reduce stress of piglets, prohibit feeding moldy and deteriorated feed, ventilate piggery and reduce ammonia concentration; Keep the pigsty dry and reduce the feeding density of pigs.

(4) Improve or improve feed quality. Astragalus polysaccharides and electrolytic multivitamins can be added to pig drinking water in daily feeding; Adding premix containing doxycycline, florfenicol, tylosin and synergist to feed can enhance the resistance of pigs and prevent secondary infection.

(5) Effective environmental sanitation and disinfection measures to reduce the chance of virus infection.

(6) Formulating and strictly implementing reasonable immunization procedures, timely immunizing pigs against diseases such as circovirus, classical swine fever and blue ear disease, regularly monitoring the antibody level of pigs, and timely handling positive pigs.

(7) Quarantine and isolation at the time of introduction. In artificial insemination pig farms, semen free from circovirus type II pollution was selected.

(8) Isolation of sick pigs, timely symptomatic treatment or elimination.