Erythromycin is ineffective against mycoplasma hominis and clindamycin is ineffective against ureaplasma urealyticum. For female pelvic inflammatory disease, many factors should be considered, and the treatment should include antibiotics against Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis and anaerobic bacteria. The combination therapy of cefoxitin+doxycycline or clarithromycin+gentamicin is recommended abroad.