20 10-20 15, which APIs are about to expire?

1, anti-AIDS drugs

The expiration date of American patent for lamivudine is 2009.5438+0 1, and there are 2 1 domestic producers (operators).

The American patent of Abacavir expired in June 2009. There are 2 domestic production (business) units.

Nevirapine has 22 production (business) units in China, and the expiration date of American patents is 2011.11.

There are 9 production (business) units of efavirenz in China, and the validity period of American patent is 20 13.5.

Indinavir has four domestic production (operation) units, and the validity period is 2011.11.

Nefinavir has five production (business) units in China, and the expiration date of American patent is 20 13. 10.

The expiration date of Amprenavir patent is 20 13. 1 1, and there are 2 domestic production (business) units.

Atazanavir has two domestic production (operation) units, and the expiration date of American patent is 20 14. 1.

2. Lipid-regulating drugs

The patent expiration date of atorvastatin in the United States is 20 15.6, and that in Europe is 20 1 1.6. There are 7 domestic production (business) units.

3, digestive system drugs

Esomeprazole has three production (business) units in China, and the expiration date of American patent is 20 14. 1.

4. Cardiovascular system

Clopidogrel patent is valid for 20 1 1. 1, and there are 25 domestic production (business) units.

5. Hypertension

The validity period of diltiazem hydrochloride (diltiazem hydrochloride) is 20 1 1.5, and there are 13 domestic production (operation) units.

6. Anti-ocular hypertension and glaucoma

The U.S. patent for Latampoulos expires on 20 1 1.3. The domestic production unit is 1 1.

The expiration date of the U.S. patent for bimatoprost is 20 12.9, and the domestic production (business) unit is 0.

The expiration date of the American patent for brinzolamide is 20 10.8, and the domestic production (business) unit is 0.

7. Parkinson's disease

The expiration date of pramipexole hydrochloride in the United States is 20 1 1.3, and there are 7 domestic production units.

8.asthma

Zaruste has nine domestic production (operation) units with the validity period of 20 10.5 in the United States.

9. Anti-acne

Adapalene has a patent expiration date of 20 10.5, and there are 36 domestic production (business) units.

10, anti-infection

There are 0 domestic production (business) units when the U.S. patent (2009. 1 1) of atrafloxacin mesylate expires.

1 1, antiemetic

There are 8 domestic production (business) units with the expiration date of the American patent of alosetron hydrochloride of 2010.

12, anticancer

The expiration date of amifostine in the United States is 20 12.7, and the domestic production (operation) unit is 13.

The expiration date of the American patent for anastrozole is 2009.5438+02, and there are 60 domestic production (business) units.

13, anti-metamorphosis

There are 9 domestic production (operation) units, and the expiration date of the U.S. patent for azelastine hydrochloride is 20 1 1. 10.

14, antitumor drugs

Carmustine has five production (business) units in China, and the expiration date of American patent is 20 10. 1.

15, cardioprotective agent

Dexrazoxan)e US patent 20 10.9 expires, and there are five domestic production (business) units.

16, nervous system medication

Modafenib has 26 production (business) units in China, and the expiration date of American patent is 20 14. 10.

17, antiepileptic drugs

The validity period of gabapentin in the United States is 20 10. 1, and there are three production (business) units in China.

18, other

The expiration date of American patent in desmopressin acetate is 20 13.6, and there are 13 domestic production (operation) units.

The patent expiration date of alendronate sodium is 20 12. 12, and there are 37 domestic production (operation) units.