1, the price and function of folic acid tablets
Silian (Folic Acid Tablet) is a low-dose folic acid supplement recommended by the state for pregnant women, which can not only effectively prevent fetal neural tube malformation, but also prevent anemia of fetus and pregnant women and reduce the birth rate of small and low birth weight infants. Then, how much is Sian (Folic Acid Tablets)? What are the functions?
Silian (Folic Acid Tablet) is used to prevent birth defects such as congenital heart disease, rabbit lip and neural tube malformation. After three years of joint research and development by China Maternal and Child Health Center, US Centers for Disease Control and Prevention, and Peking University Pharmaceutical/KLOC-0, we obtained the national new drug certificate and invention patent certificate, which were listed as "100 achievements promotion plans in ten years" by the Ministry of Health and "three major projects" by the National Family Planning Commission. At present, millions of pregnant women in China begin to take aspirin every year, and it has produced very obvious preventive effect.
Silian (Folic Acid Tablets) can be bought in major hospitals and pharmacies, but the price is different. Please consult your local pharmacy for details.
So what does Sian (Folic Acid Tablets) do?
The main functions of Sian (Folic Acid Tablets) are: 1, preventing fetal neural tube defects (anencephaly, spina bifida), and the effective rate is 85%. 2. Prevention of fetal cleft lip and palate, with an effective rate of 50%. 3. Prevent birth defects such as fetal congenital heart disease and other surface malformations. 4. Prevent anemia in pregnant women, nursing mothers and fetuses. 5. Promote the development of fetal nervous system. 6. Reduce infant mortality. 7. Reduce pregnancy reaction.
Silian (Folic Acid Tablets) Other functions: 1. Can prevent chronic cardiovascular diseases such as coronary heart disease. 2. It can prevent Alzheimer's disease and other cancers and reduce the incidence. 3. Reduce and prevent the incidence of breast cancer and cervical cancer in women. 4. Prevention and treatment of megaloblastic anemia caused by drugs.
2. The harm of folic acid supplementation.
Side effects of folic acid tablets
Folic acid is a water-soluble B vitamin composed of pteridine, p-aminobenzoic acid and glutamic acid residues, which is necessary for cell growth and reproduction. It exists in liver, kidney, yeast and green leafy vegetables such as beans, spinach, tomatoes, carrots and so on. And now it can be synthesized artificially.
Side effects of folic acid tablets
Folic acid reacts with dihydrofolate reductase and vitamin B 12 to form tetrahydrofolate (THFA), which binds to various one carbon unit (including CH3, CH2, CHO, etc.). ) forms tetrahydrofolate coenzyme, which is transferred to a carbon unit and participates in many important reactions in the body and the synthesis of nucleic acids and amino acids.
THFA forms N5, 10 methylenetetrahydrofolate under the action of serine hydroxylase, which can promote the formation of uracil nucleotide (dUMP) and thymine nucleotide (dTMP), participate in the DNA synthesis of cells, and promote cell division and maturation. In the process of DNA synthesis, deoxyuridylic acid is converted into deoxythymidylic acid, and the required methyl group is provided by methylenetetrahydrofolate. When folic acid is deficient, DNA synthesis slows down, but RNA synthesis is not affected. In this way, blood cells with large cell volume and immature nuclear development are produced in bone marrow, especially red blood cells, which can be treated in time.
Many women know that folic acid should be properly supplemented before pregnancy. At the same time, many women will also have such questions in their hearts: pregnancy is a major event for women, and folic acid should be supplemented before pregnancy. What side effects does folic acid have? Does taking folic acid produce any adverse reactions? Won't eating bad baby hurt baby? Next, let's introduce the side effects of folic acid and the matters needing attention when taking folic acid.
Side effects of folic acid
First of all, we should understand that folic acid usually has no side effects. At present, the biggest problem of taking folic acid is not the side effect of folic acid, but the problem of taking too much folic acid.
Side effects of folic acid
Folic acid is a water-soluble vitamin, which generally exceeds the minimum requirement of adults by 20 times and will not cause poisoning. However, excess folic acid is excreted from the urine.
However, if people take large doses of folic acid tablets, it may also produce toxicity. At present, women before pregnancy can generally take 400 micrograms a day, depending on the instructions of various folic acid tablets.
Taking too much folic acid will mask the early manifestations of vitamin deficiency and lead to damage to the nervous system.
Adverse reactions caused by folic acid overdose
Taking folic acid in large quantities for a long time can cause gastrointestinal symptoms such as anorexia, nausea, abdominal distension and yellow urine. Oral folic acid can quickly improve megaloblastic anemia, but it can't prevent the progress of mental damage caused by vitamin deficiency. Moreover, if folic acid is still taken in large doses, it will further reduce the vitamin content in serum and make the nerve damage irreversible.
Caution: Use synthetic folic acid with caution.
At present, the researchers' latest discovery is that the natural folic acid contained in green leafy vegetables is absorbed in the human intestine, while the synthetic folic acid is absorbed in the liver. The amount of synthetic folic acid absorbed by the liver is limited, and the unabsorbed excess synthetic folic acid will enter the blood, which may cause diseases such as leukemia and arthritis.