DIA is the abbreviation of inhibin A dimer.
1. Syntaxin is a heterodimeric protein hormone secreted by female ovarian granulosa cells and male testicular Sertoli cells. It selectively inhibits the secretion of follicle-stimulating hormone (FSH) and also has local paracrine effects on the gonads. The complete inhibin molecule is a molecule with a molecular weight of approximately 32KD, consisting of two different subunits (a subunit and b subunit) connected by a disulfide bond.
2. Inhibin is a dimeric peptide hormone produced by female ovarian granulosa cells, male Sertoli cells and various other tissues. There are two isoforms of inhibin, A and B, with the same a subunit but different beta subunits. Inhibin A is a dimer with the βA subunit, and inhibin B is a dimer with the α and BB subunits.
Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, inhibins are also thought to play a role in controlling gametogenesis, embryonic and fetal development.
3. HCG human chorionic gonadotropin is a glycoprotein hormone secreted by the trophoblast cells of the placenta. HCG is composed of two subunits, α and β. A single subunit has no biological activity and can only play a role after being combined through non-valent bonds to form a dimer.
The main function of HCG is to stimulate the conversion of the corpus luteum from the menstrual corpus luteum to the gestational corpus luteum, while promoting the continued secretion of estrogen and progesterone, maintaining the morphology of the endometrium, promoting the formation of uterine decidua, and maturing the placenta. , essential for maintaining pregnancy.