Question 1: How to crystallize mannitol? Put mannitol in water at 70 degrees and it will dissolve in a short time
Question 2: Why can’t mannitol be used after crystallization? Details It says that it can be used, but the crystals must be melted before use. You can put the bottle in hot water and shake it vigorously to melt it quickly.
It cannot be used if it is not melted, because the crystals have sharp edges and will cause damage or embolism if they enter human tissue.
Question 3: Mannitol crystallization occurs in winter. The solution is to solve the problem of mannitol crystallization in winter. In the past, if you encountered crystallized mannitol, you would put it in hot water, then take it out and shake it vigorously. This is time-consuming and labor-intensive, and even When heated and boiled, sometimes it is difficult to dissolve and cannot be completely dissolved for several hours, often causing the bottle label to be damaged or even the bottle body to break. In just one year, our hospital's pharmacy accumulated hundreds of bottles of crystallized mannitol, which could not be used clinically. Based on mannitol's high melting point and stable properties, we boldly experimented with using a high-pressure steam pot for daily disinfection. Crystalline mannitol is dissolved, but is less effective and dangerous. Mannitol is easy to crystallize when it is cold, and is often dissolved by boiling during infusion. When dissolved, the label may be damaged, fall off, or even the bottle may rupture. In addition, impurities in the water adhere to the bottle wall during boiling, which can easily affect the transparency and bring inconvenience to the inspection work. Moreover, the boiled mannitol often crystallizes again after being left alone. We use a mannitol incubator to dissolve mannitol crystals, and the effect is good ~
Question 4: How to deal with mannitol crystals? 5-minute avatar phone, mannitol incubator can constant the temperature of mannitol to 37 degrees, which is the same as human body temperature Completely close, which makes it easier for patients to accept.
Mannitol is a dehydrating agent, its function is to increase blood osmotic pressure, and the effect is reduced after crystallization. Side effects of mannitol include thrombophlebitis and anaphylactic shock. Ordinary infusion sets do not have mesh, so when mannitol crystallizes, it may cause vascular embolism and sudden death. Of course, death from anaphylactic shock cannot be ruled out. I have also encountered mannitol crystals that were fine when used by patients. The mannitol thermostat is controlled by a microcomputer and has obtained the national medical device production license. It is a patented product and uses PTC ceramic heating, which is safer and more secure!
Question 5: How to quickly cool down the mannitol crystals after they are dissolved in boiling water?
Question 6: Why does mannitol injection crystallize? How to solve it? The reason is that the room temperature is too low, which causes the saturation point of mannitol to decrease and crystals precipitate. During this season, a lot of mannitol in the hospital has crystallized! As long as the medicine does not expire and it crystallizes, it will be fine. Just boil it in water and wait until it becomes saturated again!
Question 7: How does mannitol dissolve the crystals of mannitol injection? Of course it is diluted with normal saline