Legal analysis: If the defender thinks that the reason why the defendant thinks he is innocent is invalid, or after reading the paper, the defender thinks that the evidence of the public prosecution agency is very conclusive and the evidence of guilt is conclusive, and the defendant has not truthfully stated the facts of the case to the defender, he can refuse to defend according to law. Defender can't plead guilty if defendant doesn't plead guilty.
Legal basis: Article 35 of the Criminal Procedure Law of People's Republic of China (PRC), defenders put forward materials and opinions to prove the innocence of criminal suspects and defendants, or reduce or exempt their criminal responsibilities according to facts and laws, and safeguard the legitimate rights and interests of criminal suspects and defendants. This is the regulation of the defender's defense responsibility.