Dose classification capsule
Store at room temperature, dry, dark and sealed.
Ingredients Amoxicillin 250mg Dichloropenicillin125mg.
This product is ampicillin capsules. White powder after removing capsule shell.
Pharmacological action This experiment has not been carried out, and there are no reliable references.
Pharmacological and toxicological products are compound preparations composed of amoxicillin and dicloxacillin sodium, and amoxicillin is a broad-spectrum penicillin antibody.
Dicloxacillin is an isoxazole penicillin, which is not easily destroyed by penicillinase. This product has antibacterial effect on the following bacteria in vitro.
Gram-positive bacteria: Staphylococcus aureus group A and group B hemolytic streptococcus viridis streptococcus faecalis pneumococcus.
Gram-negative bacteria: Neisseria gonorrhoeae, epidemic meningococcus and haemophilus parainfluenzae.
Anaerobic bacteria such as Salmonella, Clostridium and Actinomycetes.
The pharmacokinetics of patients with follicular non-Hodgkin's lymphoma is125,250 or 375mg/㎡ body surface area.
Toxoximab treatment, intravenous drip once a week, ***4 times, serum antibody concentration increased with the increase of dose. about
The average serum half-life after the first infusion of rituximab was 68. 1 hour in patients receiving 375mg/㎡.
Cmax was 238.7μg/ml, and the average plasma clearance rate was 0.0459L/ hour. Serum half-life after the fourth drip,
The average Cmax and plasma clearance rate were 65438 089.9 hours, 480.7 μ g/ml and 0.065438 045 liters/hour, respectively, but serum water
The variability of flatness is great. Secondly, the serum concentration of rituximab was significantly higher in patients who responded. Generally speaking, three to six.
Rituximab can still be detected in serum at 10 month. In patients with diffuse large B-cell non-Hodgkin's lymphoma, rituximab
The clearance and distribution of monoclonal antibodies bound to CHOP have not been studied.
Drug class penicillin
Drug interaction 1 benzenesulfonic acid can reduce the secretion of amoxicillin/dicloxacillin sodium by renal tubules.
The half-life of amoxicillin/dicloxacillin sodium is prolonged by 2. Allopurinol combined with ampicillin and ampicillin alone.
It is not clear whether the increase of rash is caused by allopurinol or excessive urine toxin.
There is no data that allopurinol and amoxicillin/dicloxacillin sodium can be used with amoxicillin/dicloxacillin.
Sodium should not be used with disulfiram.
Functional indications are suitable for treating (1) respiratory tract infections: acute pharyngitis, suppurative tonsillitis, acute and chronic tracheitis.
Secondary infection of bronchitis, pneumonia and cold; (2) Digestive tract infection: hepatobiliary system infection, acute gastroenteritis and typhoid fever.
Paratyphoid fever; (3) Infection of urogenital system: urethritis, cystitis, pyelonephritis, gonorrhea and chancre; (4)
Otolaryngology and oral infections: acute and chronic otitis media, periodontitis and rhinitis; (5) Bone and joint infection: osteomyelitis; (6) Others
Infection: cardiovascular infection, skin and soft tissue infection.
Indications are suitable for the treatment of (1) respiratory infections: acute pharyngitis, suppurative tonsillitis, acute and chronic tracheitis,
Secondary infection of bronchitis, pneumonia and cold; (2) Digestive tract infection: hepatobiliary system infection, acute gastroenteritis, typhoid fever,
Paratyphoid fever; (3) Infection of urogenital system: urethritis, cystitis, pyelonephritis, gonorrhea and chancre; (4) Ears
Nasopharyngeal and oral infections: acute and chronic otitis media, periodontitis and rhinitis; (5) Bone and joint infection: osteomyelitis; (6) Other senses
Infection: cardiovascular infection, skin and soft tissue infection.
Note: Side effects are mild, and a few patients may have nausea, vomiting, diarrhea and abdominal distension. Occasionally the skin itches,
Rash, etc. It can disappear by itself after stopping the drug. 1 This product is penicillin, and it has been reported that this product can cause fatal allergy.
Reaction; Skin allergy test must be carried out before penicillin is used. Please consult in detail before using amoxicillin/dicloxacillin sodium for treatment.
Ask about the allergic history of allergens such as penicillin and cephalosporin. If it happens during treatment with amoxicillin/dicloxacillin sodium.
Allergic reaction, should stop taking medicine. Severe allergic reactions need urgent treatment, such as oxygen inhalation, epinephrine use and skin intravenous infusion.
Hormones and airway patency include tracheal intubation. Use with caution in patients with a history of cephalosporin allergy. 3 have been reported
Pseudomembranous colitis occurs in patients who use various penicillins (including amoxicillin and dicloxacillin sodium)
The severity is moderate to severe. It is important to consider this situation when patients who use penicillin have diarrhea. 4 obvious
Use with caution in patients with low liver function. The hepatotoxicity of amoxicillin/dicloxacillin sodium is usually reversible. 5 single core
When patients with increased cells receive ampicillin treatment, the incidence of rash is high. So we can't give ampicillin antibiotics.
For patients with mononucleosis. Attention should be paid to the possible secondary infection of mold and bacteria. If a secondary infection occurs (usually
For Pseudomonas or Candida), the drug should be stopped and treated properly.
Administration and dosage: 375 mg each time (1capsule), three times a day, and the dosage can be increased for severe infection. Children: Dose
The number is halved.
The experiment was not carried out because of drug overdose, and there were no reliable references.
Adverse reactions have few side effects.
Drugs for children 1. Please consult a doctor or pharmacist about the dosage for children. 2. Children must use it under the supervision of adults.
Reproductive studies of pregnant and lactating women show that this product can cross the placenta, but there is no sign of fetal damage.
. There is no information about the secretion of this product in breast milk. So far, the safety of pregnant and lactating women using this product has not been confirmed.
Therefore, this product should be used only when pregnant or lactating women have no suitable choice.
Elderly patients should adjust the dosage or interval of medication according to renal function under the guidance of doctors.
Is it a prescription drug?
Oral, external use and oral administration
People who are allergic to penicillin are prohibited.