Rabeprazole sodium is a drug that inhibits secretion and is a substitute for benzimidazole. It has no anticholinergic and antihistamine properties, but it can adhere to the surface of gastric parietal cells and inhibit the secretion of gastric acid by inhibiting H+/K+-ATPase. This enzyme system is regarded as an acidic proton pump, so rabeprazole sodium, as a proton pump inhibitor in the stomach, blocks the production of gastric acid in a dose-dependent manner. Animal experiments have confirmed that rabeprazole sodium can be excreted from plasma and gastric mucosa shortly after administration. Adverse Reactions of Colloidal Bismuth After taking this product, the feces can be dark brown, but there is no other discomfort, which is a normal reaction, and the color of feces turns normal within 1-2 days after stopping taking the drug. This product is a gastric mucosal protective drug. Sol is formed in stomach after oral administration, which has strong affinity with ulcer surface and inflammatory surface, and can form protective film, isolate gastric acid, protect damaged mucosa, stimulate gastrointestinal mucosal epithelial cells to secrete mucus, and promote epithelial cells to repair themselves. This product has strong adhesion to damaged mucosa. This product can also kill Helicobacter pylori in the stomach and promote the healing of gastritis.
To sum up: the patient's intestinal symptoms are caused by colloidal bismuth, and naturally recover after stopping taking the drug!