In the 22nd year of Guangxu (1896), Synbiotics Bank set up a branch in Anton (Dandong), and then set up an agency in the Democratic People's Republic of Korea and Sinuiju, which was controlled by Russian forces, to start international exchange business. In the 26th year of Guangxu (1900), Zhou Xinyi Society was renamed Heshengyuan Branch Village. In the 30th year of Guangxu (1904), a war broke out between Japan and Russia. The following year, Russia was defeated and forced to give up its privileges in the Democratic People's Republic of Korea and re-divide its sphere of influence with Japan in the northeast. Synbiotics Bank strives for survival and development in the cracks, and has set up branches in Siping, Harbin, Qiqihar, Heihe and other places, and then developed to Japan. In the thirty-third year of Guangxu (1907), Synbiotics Kobe Branch was established in Kobe, Japan.